SCHEMBL210867

SCHEMBL210867

Cc1ccc(O)c(Cc2cc(C)c(O)c(CO)c2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.67
AMY1A P0DUB6 1/20 0.56
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
PKM P14618 1/20 0.39
ALK Q9UM73 1/20 0.38
TRPA1 O75762 1/20 0.37
HTT P42858 2/20 0.37
KLF10 Q13118 1/20 0.37
LMNA P02545 1/20 0.36
HMGB1 P09429 1/20 0.36
CXCL12 P48061 1/20 0.36
SLC5A1 P13866 1/20 0.35
SLC5A2 P31639 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CASP6 P55212 1/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30764682 0.89 AMY1A (0.65) SHBGAMY1AESR1ESR2TP53
SCHEMBL5364380 0.89 AMY1A (0.65) SHBGAMY1AESR1ESR2TP53
SCHEMBL4056593 0.88 AMY1A (0.75) SHBGAMY1AESR1ESR2TP53
SCHEMBL2386946 0.87 AMY1A (0.69) SHBGAMY1AESR1ESR2TP53
SCHEMBL30320337 0.87 AMY1A (0.69) SHBGAMY1AESR1ESR2TP53
SCHEMBL21096825 0.85 AMY1A (0.66) SHBGAMY1AESR1ESR2TP53
SCHEMBL7546172 0.84 AMY1A (0.75) SHBGAMY1AESR1ESR2TP53
SCHEMBL23864789 0.84 SHBG (0.77) SHBGAMY1AESR1ESR2PKM
SCHEMBL7522709 0.83 SHBG (0.76) SHBGAMY1AESR1ESR2ALK
SCHEMBL24541912 0.82 AMY1A (0.61) SHBGAMY1AESR1ESR2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) PCBP1, FPR2, PNKP SHBG 3146/4885AMY1A 2459/4885ESR1 4141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.