Etazepine

Etazepine

SCHEMBL2108670

CCOC1c2ccccc2C(=O)N(C)c2ccccc21

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 3/20 0.44
CES1 P23141 1/20 0.44
BRD4 O60885 2/20 0.42
MAPK7 Q13164 1/20 0.42
DRD2 P14416 1/20 0.40
HTR6 P50406 1/20 0.40
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.40
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ATM Q13315 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etazepine SCHEMBL29561205 1.00 TTR (0.44) TTRCES1BRD4MAPK7DRD2
SCHEMBL11011176 0.84 CDC25A (0.45) CES1ALDH1A1
SCHEMBL10447563 0.77 ACHE (0.46) TSHRCYP1A2
SCHEMBL22879456 0.73 TTR (0.50) TTRCES1DRD2HTR6KDM4E
SCHEMBL13964148 0.69 MEN1 (0.44) KDM4EALDH1A1HPGDNPC1TP53
SCHEMBL16127516 0.69 TTR (0.75) TTRCES1DRD2HTR6KDM4E
SCHEMBL26773614 0.69 PARP1 (0.48) TTRCES1DRD2HTR6KDM4E
SCHEMBL8506762 0.69 ALDH1A1 (0.41) CES1DRD2KDM4EALDH1A1HPGD
SCHEMBL3394177 0.68 HSD11B1 (0.39) BRD4MAPK7KDM4EALDH1A1HPGD
SCHEMBL8907599 0.68 CYP1A2 (0.38) KDM4EALDH1A1NPC1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025976-A Method for differentiating hematopoietic stem/progenitor cells into granulocytes 苏州血霁生物科技有限公司 2025-05-23 CN claimed
US-20250163379-A1 METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS HEMACELL BIOTECHNOLOGY INC. (CN) 2025-05-22 US claimed
CN-118786209-A Method for differentiating hematopoietic stem/progenitor cells into NK cells 苏州血霁生物科技有限公司 2024-10-15 CN claimed
WO-2023165503-A1 METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS 苏州血霁生物科技有限公司 2023-09-07 WO claimed
US-11666547-B2 Methods for treating cognitive deficits in a subject having schizophrenia, bipolar disorder, or psychiatric depression, and exhibiting cognitive deficits by administering an antagonist of the Na+-K+-2Cl-cation-chloride cotransporter isoform 1 (NKCC1) NORTHWESTERN UNIVERSITY (US) 2023-06-06 US claimed
US-20200405672-A1 METHODS FOR TREATING PSYCHIATRIC DISEASES AND DISORDERS AND THE SYMPTOMS THEREOF IN A SUBJECT BY ADMINISTERING AN ANTAGONIST OF THE NA+-K+-2CL- CATION-CHLORIDE COTRANSPORTER ISOFORM 1 (NKCC1) NORTHWESTERN UNIVERSITY (US) 2020-12-31 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-4551451-A Tricyclic derivatives of 5,6-dihydro-11H-dibenzo (b,e) azepin-6-one having pharmacological activity A. MENARINI S.A.S. (IT) 1985-11-05 US claimed
WO-2025129358-A1 STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES INTELGENX CORP. (CA) 2025-06-26 WO disclosed
CN-120025976-A Method for differentiating hematopoietic stem/progenitor cells into granulocytes 苏州血霁生物科技有限公司 2025-05-23 CN disclosed
US-20250163379-A1 METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS HEMACELL BIOTECHNOLOGY INC. (CN) 2025-05-22 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11666547-B2 Methods for treating cognitive deficits in a subject having schizophrenia, bipolar disorder, or psychiatric depression, and exhibiting cognitive deficits by administering an antagonist of the Na+-K+-2Cl-cation-chloride cotransporter isoform 1 (NKCC1) SLC6A1, SLC6A3, SLC6A13 TTR 3278/4885CES1 1502/4885BRD4 2216/4885
US-20200405672-A1 METHODS FOR TREATING PSYCHIATRIC DISEASES AND DISORDERS AND THE SYMPTOMS THEREOF IN A SUBJECT BY ADMINISTERING AN ANTAGONIST OF THE NA+-K+-2CL- CATION-CHLORIDE COTRANSPORTER ISOFORM 1 (NKCC1) SLC6A1, SLC6A3, SLC6A2 TTR 3520/4885CES1 1163/4885BRD4 3215/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 TTR 96/4885CES1 2157/4885BRD4 1147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.