Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089283 | 0.90 | OPRM1 (0.40) | ALDH1A1FAAHMGLLUSP2P2RX7 | |
| SCHEMBL21088529 | 0.78 | ALDH1A1 (0.43) | POLBCCR2ALDH1A1SMN1; SMN2USP2 | |
| SCHEMBL21088397 | 0.77 | USP2 (0.36) | ALDH1A1SMN1; SMN2FAAHMGLLUSP2 | |
| SCHEMBL25924019 | 0.76 | — | — | |
| SCHEMBL21089303 | 0.74 | KDM4E (0.43) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20106999 | 0.74 | CYP3A4 (0.32) | — | |
| SCHEMBL21088839 | 0.73 | KDM1A (0.41) | MGLLUSP2 | |
| SCHEMBL20106862 | 0.72 | — | — | |
| SCHEMBL20106745 | 0.72 | ITGB3 (0.30) | — | |
| SCHEMBL21088402 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |