Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089303 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL18182770 | 0.81 | KDM1A (0.40) | USP2MGLLFAAHKDM4EALDH1A1 | |
| SCHEMBL21088839 | 0.80 | KDM1A (0.41) | USP2CYP1A2CYP2C9CYP2C19MGLL | |
| SCHEMBL21088529 | 0.79 | ALDH1A1 (0.43) | USP2CYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL21088780 | 0.77 | POLB (0.39) | USP2MGLLFAAHALDH1A1HPGD | |
| SCHEMBL21088634 | 0.75 | GPR119 (0.38) | USP2CYP1A2CYP2C9CYP2C19MGLL | |
| SCHEMBL21089283 | 0.73 | OPRM1 (0.40) | USP2CYP1A2CYP2C9CYP2C19MGLL | |
| SCHEMBL25924019 | 0.71 | — | — | |
| SCHEMBL21089292 | 0.71 | TSHR (0.45) | USP2CYP1A2ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL21088890 | 0.69 | NR1I2 (0.30) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |