Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088839 | 0.90 | KDM1A (0.41) | CYP3A4KCNH2GPR119KDM1A | |
| SCHEMBL21088397 | 0.88 | USP2 (0.36) | KDM4ECYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL21088529 | 0.85 | ALDH1A1 (0.43) | CYP3A4ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18182290 | 0.79 | KDM1A (0.42) | KDM4ECYP3A4ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21088634 | 0.78 | GPR119 (0.38) | CYP3A4KCNH2GPR119SMN1; SMN2 | |
| SCHEMBL21089292 | 0.76 | TSHR (0.45) | CYP3A4KCNH2ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL25455558 | 0.76 | CXCR3 (0.37) | KDM4ECXCR3CHKACYP3A4ALDH1A1 | |
| SCHEMBL25455588 | 0.76 | RAB9A (0.40) | KDM4EKCNH2GPR119ALDH1A1MAPT | |
| SCHEMBL21089283 | 0.75 | OPRM1 (0.40) | CYP3A4ALDH1A1 | |
| SCHEMBL21088780 | 0.74 | POLB (0.39) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |