Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088780 | 0.90 | POLB (0.39) | FAAHMGLLP2RX7USP2ALDH1A1 | |
| SCHEMBL21088529 | 0.76 | ALDH1A1 (0.43) | USP2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21089303 | 0.75 | KDM4E (0.43) | CYP3A4ALDH1A1 | |
| SCHEMBL25924019 | 0.74 | — | — | |
| SCHEMBL21088839 | 0.73 | KDM1A (0.41) | MGLLUSP2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21088397 | 0.73 | USP2 (0.36) | FAAHMGLLUSP2CYP1A2CYP3A4 | |
| SCHEMBL20106999 | 0.72 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL21088969 | 0.72 | OPRM1 (0.42) | OPRM1CHRM2CACNA1FCHRM1DRD2 | |
| SCHEMBL20106745 | 0.71 | ITGB3 (0.30) | — | |
| SCHEMBL21088402 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |