Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088867 | 0.87 | HTR4 (0.35) | DRD2HTR2CKDM1AHTR4 | |
| SCHEMBL25924094 | 0.87 | OPRM1 (0.30) | — | |
| SCHEMBL20107004 | 0.81 | KDM1A (0.30) | KDM1A | |
| SCHEMBL19873928 | 0.78 | DRD2 (0.31) | DRD2HTR2C | |
| SCHEMBL21088777 | 0.75 | KDM1A (0.40) | KDM1A | |
| SCHEMBL25923922 | 0.75 | — | — | |
| SCHEMBL21089313 | 0.73 | EPHX2 (0.35) | DRD2KDM1A | |
| SCHEMBL25923917 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL25923913 | 0.73 | KDM1A (0.33) | KDM1A | |
| SCHEMBL21088369 | 0.73 | POLB (0.38) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |