Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 3/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088467 | 0.87 | CNR1 (0.37) | EPHX2CNR1SMN1; SMN2CTSKDRD2 | |
| SCHEMBL21088332 | 0.79 | EPHX2 (0.33) | EPHX2CNR1SMN1; SMN2 | |
| SCHEMBL21088777 | 0.79 | KDM1A (0.40) | KDM1A | |
| SCHEMBL25923992 | 0.77 | L3MBTL1 (0.40) | SMN1; SMN2KDM1A | |
| SCHEMBL20106807 | 0.76 | EHMT2 (0.44) | EPHX2SMN1; SMN2CCR2 | |
| SCHEMBL21088950 | 0.73 | DRD2 (0.31) | DRD2KDM1A | |
| SCHEMBL25924094 | 0.72 | OPRM1 (0.30) | — | |
| SCHEMBL25923869 | 0.72 | NPSR1 (0.33) | KDM1A | |
| SCHEMBL20107004 | 0.72 | KDM1A (0.30) | KDM1A | |
| SCHEMBL20106792 | 0.72 | KDM1A (0.44) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |