Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CCR3 | P51677 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12813733 | 0.83 | KDM1A (0.70) | KCNH2KDM1ADRD2MAOBHTR2A | |
| SCHEMBL12813735 | 0.83 | KDM1A (0.70) | KCNH2KDM1ADRD2MAOBHTR2A | |
| SCHEMBL14032714 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CCR3HRH1KCNH2CXCR4 | |
| SCHEMBL21101178 | 0.79 | ATM (0.62) | ALDH1A1CXCR4POLBKMT2ASIGMAR1 | |
| SCHEMBL14032449 | 0.78 | ACHE (0.60) | ALDH1A1CCR3HRH1KCNH2DRD2 | |
| SCHEMBL28169202 | 0.78 | CXCR4 (0.68) | ALDH1A1CCR3CXCR4KDM1AMAOB | |
| SCHEMBL21101342 | 0.78 | CYP2D6 (0.60) | CCR3HRH1KCNH2CXCR4KDM1A | |
| SCHEMBL21101005 | 0.77 | KDM1A (0.50) | KCNH2CXCR4KDM1ADRD2MAOB | |
| SCHEMBL21101104 | 0.77 | SIGMAR1 (0.50) | ALDH1A1CCR3CXCR4KDM1ADRD2 | |
| SCHEMBL19725557 | 0.76 | KDM1A (0.67) | CXCR4KDM1ADRD2MAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2688568-B1 | CYCLOPROPYLAMINES AS LSD1 INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2019-06-19 | — | — | EP | disclosed |