Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Cocarboxylase. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.96 |
| ▸ | TKT | P29401 | 7/20 | 0.83 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PPP5C | P53041 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cocarboxylase SCHEMBL27898926 | 0.99 | LMNA (0.98) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL21111 | 0.99 | LMNA (0.98) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL8923435 | 0.99 | LMNA (0.98) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL23151784 | 0.98 | LMNA (0.96) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL662896 | 0.98 | LMNA (0.96) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL30192281 | 0.98 | LMNA (1.00) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL80028 | 0.98 | LMNA (1.00) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9766249 | 0.97 | LMNA (0.94) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL478202 | 0.97 | LMNA (0.94) | LMNATKTTDP1HSP90AA1ALDH1A1 | |
| Cocarboxylase SCHEMBL23151785 | 0.97 | LMNA (0.98) | LMNATKTTDP1HSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4537826-A1 | METHOD FOR TREATING MENTAL DISEASES | Shanghai Raising Pharmaceutical Co., Ltd. (CN) | 2025-04-16 | — | — | EP | claimed |
| CN-119384278-A | Method for treating mental diseases | 上海日馨医药科技股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-117756852-A | Preparation method of cocarboxylase tetrahydrate | 燃点(南京)生物医药科技有限公司 | 2024-03-26 | — | — | CN | claimed |
| WO-2023236781-A1 | METHOD FOR TREATING MENTAL DISEASES | 上海日馨医药科技股份有限公司 | 2023-12-14 | — | — | WO | claimed |
| CN-116270503-A | Preparation method of 12 compound vitamins for injection | 天津汉瑞药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-113402555-B | Preparation method of cocarboxylase and tetrahydrate or salt thereof | 上海医药工业研究院 | 2022-12-30 | — | — | CN | claimed |
| CN-113402555-A | Preparation method of cocarboxylase and tetrahydrate or salt thereof | 上海医药工业研究院 | 2021-09-17 | — | — | CN | claimed |
| CN-111007162-A | Method for simultaneously detecting contents of two impurities of cocarboxylase tetrahydrate | 济南康和医药科技有限公司 | 2020-04-14 | — | — | CN | claimed |
| CN-110988233-A | Method for detecting impurity A content of cocarboxylase tetrahydrate | 济南康和医药科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-108634093-A | It is a kind of can strengthen immunity piglet feed | 南安市创培电子科技有限公司 | 2018-10-12 | — | — | CN | claimed |
| US-20130287757-A1 | COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | MEDESTEA INTERNAZIONALE S.P.A. (IT) | 2013-10-31 | — | — | US | claimed |
| CN-103351407-A | Novel crystal form of cocarboxylase tetrahydrate | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2013-10-16 | — | — | CN | claimed |
| WO-2012095702-A1 | A COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | MEDESTEA INTERNAZIONALE S.P.A. (IT) | 2012-07-19 | — | — | WO | claimed |
| CN-102068453-B | Stable complex vitamin composition and preparation method thereof | BEIJING JINGWEI XINKANG MEDICAL TECHNOLOGY CO LTD | 2012-01-11 | — | — | CN | claimed |
| CN-102068453-A | Stable complex vitamin composite and preparation method thereof | BEIJING JINGWEI XINKANG MEDICAL TECHNOLOGY CO LTD | 2011-05-25 | — | — | CN | claimed |
| CN-101787049-B | Novel crystal form of cocarboxylase tetrahydrate and preparation method thereof | BEIJING JINGWEI XINKANG MED TECH CO LTD | 2011-04-20 | — | — | CN | claimed |
| CN-101787048-B | Preparation method of cocarboxylase tetrahydrate | BEIJING JINGWEI XINKANG MED TECH CO LTD | 2011-04-06 | — | — | CN | claimed |
| CN-101787049-A | Novel crystal form of cocarboxylase tetrahydrate and preparation method thereof | BEIJING JINGWEI XINKANG MED TE | 2010-07-28 | — | — | CN | claimed |
| CN-101787048-A | Preparation method of cocarboxylase tetrahydrate | BEIJING JINGWEI XINKANG MED TE | 2010-07-28 | — | — | CN | claimed |
| CN-101711769-A | Stable injection composite of 12 complex vitamins and preparation method thereof | BEIJING JINGWEIXINKANG PHARMAC | 2010-05-26 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130287757-A1 | COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | CUTA, UNG, MMP1 | LMNA 3710/4885TKT 661/4885TDP1 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.