Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003733 | 0.95 | LMNA (0.38) | LMNAALOX15HSD17B10 | |
| SCHEMBL3189966 | 0.95 | LMNA (0.38) | LMNAALOX15HSD17B10 | |
| SCHEMBL22193118 | 0.74 | CYP2C9 (0.34) | — | |
| SCHEMBL345324 | 0.74 | LMNA (0.50) | LMNAALOX15HSD17B10 | |
| SCHEMBL1661967 | 0.74 | LMNA (0.50) | LMNAALOX15HSD17B10 | |
| SCHEMBL316986 | 0.74 | LMNA (0.50) | LMNAALOX15HSD17B10 | |
| SCHEMBL21191374 | 0.73 | LMNA (0.36) | LMNA | |
| SCHEMBL16625654 | 0.73 | LMNA (0.36) | LMNAALOX15HSD17B10 | |
| SCHEMBL22193124 | 0.73 | — | — | |
| SCHEMBL28414100 | 0.72 | LMNA (0.40) | LMNAALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078219-B2 | Method for producing coordinatively unsaturated metal-organic framework and coordinatively unsaturated metal-organic framework | TOYOTA JIDOSHA KABUSHIKI KAISHA | 2021-08-03 | — | — | US | disclosed |
| US-11008347-B2 | Metal-organic framework and method of producing the same | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2021-05-18 | — | — | US | disclosed |
| US-10702851-B2 | Metal-organic framework and method of manufacturing the same | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2020-07-07 | — | — | US | disclosed |
| US-20190194232-A1 | METAL-ORGANIC FRAMEWORK AND METHOD OF PRODUCING THE SAME | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10702851-B2 | Metal-organic framework and method of manufacturing the same | TRIM4, TRIM24, PICALM | LMNA 3841/4885ALOX15 2360/4885HSD17B10 2059/4885 |
| US-11078219-B2 | Method for producing coordinatively unsaturated metal-organic framework and coordinatively unsaturated metal-organic framework | TRPM8, F8, SLC16A8 | LMNA 2331/4885ALOX15 533/4885HSD17B10 4084/4885 |
| US-20190194232-A1 | METAL-ORGANIC FRAMEWORK AND METHOD OF PRODUCING THE SAME | TRIM4, MDM4, TRIM59 | LMNA 3781/4885ALOX15 3412/4885HSD17B10 3906/4885 |
| US-11008347-B2 | Metal-organic framework and method of producing the same | TRIM4, MDM4, TRIM59 | LMNA 3781/4885ALOX15 3412/4885HSD17B10 3906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.