Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16265321 | 0.83 | AKR1C3 (0.36) | GSTP1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL711834 | 0.80 | GSTP1 (0.57) | GSTP1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL21134077 | 0.76 | APP (0.40) | CYP1A2CYP3A4CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL18464128 | 0.76 | GABBR2 (0.30) | — | |
| SCHEMBL20806198 | 0.74 | ESR1 (0.37) | CYP1A2HSD17B1HSD17B2ALOX5APFEN1 | |
| SCHEMBL18464809 | 0.73 | CYP1A2 (0.46) | GSTP1CYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL24270298 | 0.73 | GSTP1 (0.52) | GSTP1CYP11B1CYP11B2CYP1A2CYP2C9 | |
| SCHEMBL22300013 | 0.71 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP1A2NPC1RAB9A | |
| SCHEMBL17694325 | 0.71 | PTPN11 (0.45) | CYP3A4CYP2D6 | |
| SCHEMBL25070289 | 0.70 | HSD17B1 (0.47) | GSTP1CYP11B1CYP11B2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230053362-A1 | DICHROIC DYE COMPOSITION | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-10344217-B2 | Device for controlling the passage of energy, containing a dichroic dye compound | MERCK PATENT GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344217-B2 | Device for controlling the passage of energy, containing a dichroic dye compound | CRY1, SLC25A1, CRY2 | GSTP1 1419/4885CYP11B1 499/4885CYP11B2 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.