SCHEMBL21135361

SCHEMBL21135361

Cc1c(N)c(C)c(S(=O)(=O)Nc2ccc(C(N)=O)cc2)c(C)c1N

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.74
ALDH1A1 P00352 4/20 0.58
BRD4 O60885 1/20 0.48
MAPT P10636 2/20 0.48
RAB9A P51151 1/20 0.48
HTT P42858 2/20 0.48
GAA P10253 2/20 0.48
LMNA P02545 1/20 0.48
MAPK1 P28482 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
POLB P06746 3/20 0.46
TSHR P16473 2/20 0.44
HPGD P15428 1/20 0.43
TP53 P04637 1/20 0.43
GFER P55789 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21104597 0.88 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1MAPTRAB9AHTT
SCHEMBL21104492 0.83 GAA (0.69) SMN1; SMN2ALDH1A1MAPTRAB9AHTT
SCHEMBL21135669 0.79 KMT2A (0.51) SMN1; SMN2ALDH1A1MAPTHTTGAA
SCHEMBL21135380 0.78 CA2 (0.59) SMN1; SMN2HTTGAALMNAMAPK1
SCHEMBL21135379 0.77 MAPT (0.56) SMN1; SMN2ALDH1A1MAPTRAB9AHTT
SCHEMBL4573407 0.75 HPGD (0.74) SMN1; SMN2ALDH1A1BRD4MAPTRAB9A
SCHEMBL6318007 0.75 HPGD (0.74) SMN1; SMN2ALDH1A1BRD4MAPTRAB9A
SCHEMBL21135670 0.74 WDR5 (0.60) ALDH1A1LMNAMEN1KMT2APOLB
SCHEMBL2026762 0.73 HPGD (0.57) SMN1; SMN2ALDH1A1HTTLMNAHPGD
SCHEMBL24586935 0.72 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1BRD4HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10717706-B2 M-phenylenediamine compound and method for producing polymer compound using same FUJIFILM CORPORATION (JP) 2020-07-21 US disclosed
US-20190177270-A1 NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177270-A1 NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME PNMT, PRMT9, HRH3 SMN1; SMN2 3765/4885ALDH1A1 3083/4885BRD4 245/4885
US-10717706-B2 M-phenylenediamine compound and method for producing polymer compound using same PNMT, HRH3, PRMT9 SMN1; SMN2 3554/4885ALDH1A1 3143/4885BRD4 346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.