SCHEMBL21135669

SCHEMBL21135669

Cc1c(N)c(C)c(S(=O)(=O)Nc2ccccc2)c(C)c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 3/20 0.51
CA12 O43570 3/20 0.51
CA9 Q16790 3/20 0.51
KEAP1 Q14145 3/20 0.50
IL1RN P18510 1/20 0.50
ERAP1 Q9NZ08 1/20 0.50
POLB P06746 1/20 0.47
MEN1 O00255 2/20 0.47
PKM P14618 2/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 2/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
HTR6 P50406 1/20 0.44
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21104492 0.83 GAA (0.69) KMT2ACA1CA2POLBMEN1
SCHEMBL21104597 0.82 SMN1; SMN2 (0.57) KMT2ACA1CA2CA12CA9
SCHEMBL21135380 0.81 CA2 (0.59) KMT2ACA1CA2CA12CA9
SCHEMBL21135670 0.81 WDR5 (0.60) KMT2APOLBMEN1ALDH1A1LMNA
SCHEMBL21135379 0.80 MAPT (0.56) CA1CA2POLBALDH1A1GAA
SCHEMBL25749442 0.80 LMNA (0.70) KMT2ACA1CA2CA12CA9
SCHEMBL21135361 0.79 SMN1; SMN2 (0.74) KMT2APOLBMEN1ALDH1A1GAA
SCHEMBL21135671 0.77 KMT2A (0.72) KMT2APOLBMEN1ALDH1A1GAA
SCHEMBL23141159 0.76 KMT2A (0.49) KMT2ACA1CA2CA12CA9
SCHEMBL812919 0.73 TSHR (0.70) KMT2ACA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10717706-B2 M-phenylenediamine compound and method for producing polymer compound using same FUJIFILM CORPORATION (JP) 2020-07-21 US disclosed
US-20190177270-A1 NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177270-A1 NOVEL M-PHENYLENEDIAMINE COMPOUND AND METHOD FOR PRODUCING POLYMER COMPOUND USING SAME PNMT, PRMT9, HRH3 KMT2A 589/4885CA1 4252/4885CA2 4713/4885
US-10717706-B2 M-phenylenediamine compound and method for producing polymer compound using same PNMT, HRH3, PRMT9 KMT2A 505/4885CA1 3970/4885CA2 4623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.