Glycolic Acid

Glycolic Acid

SCHEMBL21145147

CCCN(CCC)CCC.O=C(O)CO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
CA2 P00918 1/20 0.44
FFAR3 O14843 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
TDP1 Q9NUW8 4/20 0.39
EYA2 O00167 1/20 0.39
APP P05067 1/20 0.39
ACE P12821 1/20 0.39
KDM5A P29375 3/20 0.38
TSHR P16473 6/20 0.38
ALOX15 P16050 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
ADRA2A P08913 1/20 0.38
DRD1 P21728 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL3410973 0.86 FFAR3 (0.59) CA12CA9CA2FFAR3HDAC3
Bicarbonate SCHEMBL5875232 0.85 CA12 (0.50) CA12CA9CA2FFAR3HDAC3
Bicarbonate SCHEMBL5875239 0.85 CA12 (0.50) CA12CA9CA2FFAR3HDAC3
SCHEMBL26306484 0.84 TDP1 (0.55) CA12CA9CA2FFAR3HDAC3
Malonic Acid SCHEMBL5874653 0.83 LDHA (0.50) CA12CA9CA2FFAR3HDAC3
Succinic Acid SCHEMBL5874689 0.83 FFAR3 (0.55) FFAR3HDAC3HDAC1HDAC2HDAC8
Malonic Acid SCHEMBL5874646 0.83 LDHA (0.50) CA12CA9CA2FFAR3HDAC3
Succinic Acid SCHEMBL5874698 0.83 FFAR3 (0.55) FFAR3HDAC3HDAC1HDAC2HDAC8
Oxalic Acid SCHEMBL5874925 0.82 CA12 (0.48) CA12CA9CA2FFAR3HDAC3
Acetic Acid SCHEMBL5571031 0.82 CA12 (0.48) CA12CA9CA2FFAR3HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 CA12 194/4885CA9 618/4885CA2 1027/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK CA12 564/4885CA9 1797/4885CA2 804/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA CA12 188/4885CA9 385/4885CA2 732/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 CA12 136/4885CA9 225/4885CA2 250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.