Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 13/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.46 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 4/20 | 0.44 |
| ▸ | KIT | P10721 | 3/20 | 0.44 |
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676911 | 0.89 | FGFR4 (0.66) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21153989 | 0.87 | LCK (0.47) | FGFR4LCKKITSRCKDR | |
| SCHEMBL22781190 | 0.85 | FGFR4 (0.56) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21153337 | 0.85 | FGFR4 (0.57) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL21252170 | 0.84 | P2RX3 (0.40) | FGFR4FGFR1FGFR2FGFR3KDR | |
| SCHEMBL19943434 | 0.80 | LCK (0.53) | FGFR4LCKKITSRCKDR | |
| SCHEMBL21153914 | 0.80 | FGFR4 (0.51) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL19943152 | 0.78 | KDM4E (0.47) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL15412791 | 0.76 | FGFR4 (0.69) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 | |
| SCHEMBL29385382 | 0.76 | FGFR4 (0.69) | FGFR4FGFR1FGFR2FGFR3RPS6KB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508482-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR AND USE THEREOF | Nanjing Transthera Biosciences Co. Ltd. (CN) | 2019-07-10 | — | — | EP | disclosed |