SCHEMBL211598

SCHEMBL211598

CCOC(=O)c1nc2ccccc2s1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
SMN1; SMN2 Q16637 6/20 0.64
RAB9A P51151 7/20 0.59
NPC1 O15118 6/20 0.59
MAPT P10636 4/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
KDM4E B2RXH2 2/20 0.58
GAA P10253 1/20 0.58
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56
CASP1 P29466 1/20 0.56
MAPK1 P28482 3/20 0.56
HPGD P15428 1/20 0.54
LMNA P02545 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
CYP2C9 P11712 1/20 0.52
NFKB1 P19838 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzo[D]Thiazole SCHEMBL15385218 0.89 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL11359283 0.87 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL10009486 0.85 MAPT (0.63) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL10432439 0.84 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL3401020 0.82 MAPK1 (0.64) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL19357044 0.82 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL4345364 0.82 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL17038164 0.82 PTPN1 (0.59) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL17038135 0.81 SMN1; SMN2 (0.54) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT
SCHEMBL2174930 0.81 CYP2C9 (0.56) ALDH1A1SMN1; SMN2RAB9ANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 CN claimed
US-10655015-B2 Tire crumb-based bitumen polymer for producing a lower viscosity asphalt with improved tolerance to high temperatures Argopro Group LLC (US) 2020-05-19 US claimed
US-20200095424-A1 TIRE CRUMB-BASED BITUMEN POLYMER FOR PRODUCING A LOWER VISCOSITY ASPHALT WITH IMPROVED TOLERANCE TO HIGH TEMPERATURES Argopro Group LLC 2020-03-26 US claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
US-8586759-B2 Methods and systems for synthesis of a D-aminoluciferin precursor and related compounds LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2013-11-19 US claimed
US-20110224442-A1 METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (LLNS) 2011-09-15 US claimed
CN-122059901-A 1,3, 4-Oxadiazole compound and preparation method and application thereof 成都大学 2026-05-19 CN disclosed
US-20250313564-A1 ACIDIC SALT OR CRYSTAL FORM OF NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2025-10-09 US disclosed
EP-4547247-A2 DEUBIQUITINASE INHIBITORS AND METHODS OF USE THEREOF Dana-Farber Cancer Institute, Inc. (US) 2025-05-07 EP disclosed
EP-4219460-B1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS SITARI PHARMA INC (US) 2025-02-26 EP disclosed
US-20250011324-A1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS SITARI PHARMA, INC., 2025-01-09 US disclosed
EP-4471032-A1 ACIDIC SALT OR CRYSTAL FORM OF NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2024-12-04 EP disclosed
US-20030073707-A1 Quinuclidine-substituted hetero-bicyclic aromatic compounds for the treatment of disease PHARMACIA & UPJOHN COMPANY 2003-04-17 US disclosed
WO-2002100858-A2 QUINUCLIDINE-SUBSTITUTED HETEROAROMATIC COMPOUNDS AS LIGANDS AT NICOTINIC ACETYLCHOLINE RECEPTORS PHARMACIA & UPJOHN COMPANY (US) 2002-12-19 WO disclosed
US-5565445-A ANTIBIOTICS, USEFUL AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS OR STAPHYLOCOCCUS EPIDERMIDIS AND METHICILLIN RESITANT COAGULASE NEGATIVE STAPHYLOCOCCI MERCK & CO., INC. (US) 1996-10-15 US disclosed
US-5541176-A ANTIBIOTICS, USEFUL AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS MERCK & CO., INC. (US) 1996-07-30 US disclosed
US-5538964-A ANTIBIOTICS FOR BACTERICIDES MERCK & CO., INC. (US) 1996-07-23 US disclosed
EP-0395388-A2 Image forming method KONICA CORPORATION (JP) 1990-10-31 EP disclosed
EP-0315155-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073707-A1 Quinuclidine-substituted hetero-bicyclic aromatic compounds for the treatment of disease NAT1, UGT1A1, SLC10A1 ALDH1A1 335/4885SMN1; SMN2 1802/4885RAB9A 489/4885
US-20110224442-A1 METHODS AND SYSTEMS FOR SYNTHESIS OF A D-AMINOLUCIFERIN PRECURSOR AND RELATED COMPOUNDS HCCS, HLCS, GLUL ALDH1A1 2394/4885SMN1; SMN2 4724/4885RAB9A 4063/4885
US-20250011324-A1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS TGM2, TGM3, TGM1 ALDH1A1 4148/4885SMN1; SMN2 2176/4885RAB9A 2492/4885
US-20250313564-A1 ACIDIC SALT OR CRYSTAL FORM OF NITROGEN-CONTAINING FUSED RING DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF NR5A1, HSD17B11, CYP17A1 ALDH1A1 901/4885SMN1; SMN2 4839/4885RAB9A 1230/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR ALDH1A1 4757/4885SMN1; SMN2 4265/4885RAB9A 1863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.