SCHEMBL21165373

SCHEMBL21165373

Cc1ccc(Nc2ccc(C(c3ccc(NC(C)C(C)C)cc3)c3ccc(Nc4ccc(C)cc4)c4ccccc34)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 4/20 0.35
GAA P10253 4/20 0.35
MAPT P10636 4/20 0.35
RECQL P46063 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
TSHR P16473 2/20 0.35
ALOX12 P18054 2/20 0.35
HSD17B10 Q99714 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
ATM Q13315 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 3/20 0.34
POLB P06746 2/20 0.34
NTSR1 P30989 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165374 0.90 HPGD (0.46) HPGDTDP1GAAMAPTRECQL
SCHEMBL12206075 0.77 KDM1A (0.44) HPGDTDP1GAAMAPTL3MBTL1
SCHEMBL15960969 0.75 HPGD (0.44) HPGDTDP1GAAMAPTRECQL
SCHEMBL17953189 0.74 KDM1A (0.40) HPGDTDP1GAAMAPTL3MBTL1
SCHEMBL21165197 0.74 RAPGEF4 (0.42) HPGDTDP1GAAMAPTRECQL
SCHEMBL21165036 0.73 RAPGEF4 (0.47) KDM1A
SCHEMBL15960960 0.73 MMP2 (0.40) HPGDTDP1GAAMAPTRECQL
SCHEMBL21165052 0.72 RAPGEF4 (0.43) TDP1GAAMAPTRECQLKMT2A
SCHEMBL224751 0.72 KDM1A (0.46) HPGDTDP1GAAMAPTRECQL
SCHEMBL15960962 0.72 RAB9A (0.50) HPGDTDP1GAAMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 HPGD 4062/4885TDP1 3830/4885GAA 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.