Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22699878 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL22705422 | 0.92 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL22699903 | 0.88 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23072531 | 0.88 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18669011 | 0.84 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18686174 | 0.80 | ADRA1A (0.41) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL24938343 | 0.80 | ADRA1A (0.41) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1054349 | 0.76 | HCAR2 (0.53) | ALDH1A1CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL22699890 | 0.76 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL22699874 | 0.75 | CTSK (0.39) | ALDH1A1CYP3A4CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190218168-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | XWPharma Ltd. (KY) | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218168-A1 | PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF | GABRB3, GABRB2, GABRB1 | ALDH1A1 736/4885L3MBTL1 1789/4885CYP3A4 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.