Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 11/20 | 0.43 |
| ▸ | GSK3B | P49841 | 7/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 6/20 | 0.42 |
| ▸ | CLK2 | P49760 | 6/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.42 |
| ▸ | CDK2 | P24941 | 5/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 5/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 5/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 4/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 4/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.42 |
| ▸ | CDC7 | O00311 | 4/20 | 0.42 |
| ▸ | PAK4 | O96013 | 4/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 4/20 | 0.42 |
| ▸ | CDK7 | P50613 | 4/20 | 0.42 |
| ▸ | CDK9 | P50750 | 4/20 | 0.42 |
| ▸ | PRKX | P51817 | 4/20 | 0.42 |
| ▸ | HIPK2 | Q9H2X6 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21170346 | 0.91 | MAPK1 (0.48) | MAPK1GSK3BDAPK3CLK2CDK5 | |
| SCHEMBL21170450 | 0.86 | CDC7 (0.38) | MAPK1GSK3BDAPK3CLK2CDK5 | |
| SCHEMBL21170453 | 0.85 | NTRK1 (0.44) | MAPK1GSK3BCLK2DYRK1ALRRK2 | |
| SCHEMBL21170135 | 0.84 | MAPK1 (0.38) | MAPK1CDK2CDK9RAB9A | |
| SCHEMBL21170338 | 0.83 | PSEN1 (0.39) | MAPK1CDK2CDK9RAB9A | |
| SCHEMBL21170309 | 0.82 | MAPK1 (0.38) | MAPK1DAPK3CLK2CDK5DYRK1A | |
| SCHEMBL2566386 | 0.82 | DAPK3 (0.44) | MAPK1GSK3BDAPK3CLK2CDK5 | |
| SCHEMBL21170049 | 0.82 | DYRK1A (0.38) | MAPK1GSK3BDAPK3CLK2CDK5 | |
| SCHEMBL21170243 | 0.82 | MAPK1 (0.41) | MAPK1DYRK1APIM1CDC7CDK9 | |
| SCHEMBL21170454 | 0.81 | CCNT1 (0.36) | MAPK1DYRK1ACDK2CDK9MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3127541-B1 | CERTAIN AMINO-PYRIDAZINES, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | CYTOKINETICS INC (US) | 2019-07-17 | — | — | EP | disclosed |