SCHEMBL2117699

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5798393	1.00	KCNQ3 (0.42)	KCNQ3KCNQ2KCNE1KCNQ1KCNQ5
	SCHEMBL5799965	0.84	KCNQ3 (0.42)	KCNQ3KCNQ2KCNE1KCNQ1MAOB
	SCHEMBL5799966	0.84	KCNQ3 (0.42)	KCNQ3KCNQ2KCNE1KCNQ1MAOB
	SCHEMBL2476170	0.83	CES2 (0.50)	KCNQ3KCNQ2KCNE1KCNQ1KCNQ5
	SCHEMBL2476167	0.83	CES2 (0.50)	KCNQ3KCNQ2KCNE1KCNQ1KCNQ5
	SCHEMBL8249580	0.83	CES2 (0.50)	KCNQ3KCNQ2KCNE1KCNQ1KCNQ5
	SCHEMBL11774103	0.81	TSHR (0.50)	TSHRMAPT
	SCHEMBL5798624	0.81	TSHR (0.50)	TSHRMAPT
	SCHEMBL5798622	0.81	TSHR (0.50)	TSHRMAPT
	SCHEMBL22394813	0.78	KDM1A (0.45)	KCNQ3KCNQ2KCNE1KCNQ1KCNQ5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.