Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26422946 | 0.77 | SMN1; SMN2 (0.37) | TRPA1HTTMAPTALDH1A1GAA | |
| SCHEMBL16736618 | 0.71 | TSHR (0.57) | TSHRRORCTRPA1MAPTMAPK1 | |
| SCHEMBL24685760 | 0.67 | PNMT (0.39) | TSHRRORCTRPA1HTTMAPT | |
| SCHEMBL26422970 | 0.65 | ALOX15 (0.40) | TRPA1MAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL21973237 | 0.64 | TRPA1 (0.37) | TRPA1MAPTMAPK1ALDH1A1GAA | |
| SCHEMBL7514265 | 0.62 | TRPA1 (0.42) | TRPA1MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL22897562 | 0.61 | ALDH1A1 (0.57) | HTTMAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL25442163 | 0.61 | SLC6A2 (0.34) | TSHRTRPA1MAPTALDH1A1GAA | |
| SCHEMBL9735709 | 0.61 | CYP1A2 (0.43) | TSHRTRPA1MAPTMAPK1TDP1 | |
| SCHEMBL20982212 | 0.60 | TRPA1 (0.41) | RORCTRPA1MAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141153-A1 | INDOLAMINE 2,3-DIOXYGENASE INHIBITOR AND USE THEREOF | 杭州阿诺生物医药科技有限公司 | 2019-07-25 | — | — | WO | disclosed |