Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 10/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | FOS | P01100 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | JUN | P05412 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26080097 | 0.76 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1KDM4ETP53 | |
| SCHEMBL23717895 | 0.73 | MEN1 (0.50) | MEN1KMT2AALDH1A1TP53MAPK1 | |
| SCHEMBL26422946 | 0.71 | SMN1; SMN2 (0.37) | MEN1CYP3A4KMT2AALDH1A1RECQL | |
| SCHEMBL21212233 | 0.69 | NPC1 (0.53) | ALOX12ALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL26080323 | 0.68 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL26968733 | 0.67 | LMNA (0.48) | ALOX15ALOX12MEN1CYP3A4KMT2A | |
| SCHEMBL20428090 | 0.66 | ALOX15 (0.38) | ALOX15ALOX12MEN1CYP3A4KMT2A | |
| SCHEMBL24324875 | 0.65 | TRPA1 (0.41) | ALOX15ALOX12MEN1CYP3A4KMT2A | |
| SCHEMBL21185398 | 0.65 | TSHR (0.34) | MEN1KMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL18930369 | 0.64 | TRPA1 (0.43) | ALOX12MEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | ALOX15 4304/4885ALOX12 4360/4885MEN1 2845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.