SCHEMBL21185990

SCHEMBL21185990

Clc1ccc2oc3nc4c5ccc(-c6ccccc6)cc5c5cc(-c6ccccc6)ccc5c4nc3c2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.43
TNKS O95271 1/20 0.43
PIM1 P11309 3/20 0.42
PIM3 Q86V86 3/20 0.42
PIM2 Q9P1W9 3/20 0.42
CSNK2A2 P19784 2/20 0.42
CSNK2B P67870 2/20 0.42
CASP3 P42574 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
KMT2A Q03164 3/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
MEN1 O00255 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
TBK1 Q9UHD2 1/20 0.40
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21185950 0.95 ADORA3 (0.43) ADORA3TNKSPIM1PIM3PIM2
SCHEMBL21185987 0.88 TNKS (0.40) TNKSPIM1PIM3PIM2CSNK2A2
SCHEMBL21185979 0.86 GABRP (0.43) PIM1PIM3PIM2CSNK2A2CSNK2B
SCHEMBL30929917 0.85 KMT2A (0.46) ADORA3TNKSPIM1PIM3PIM2
SCHEMBL21176404 0.85 KMT2A (0.46) ADORA3TNKSPIM1PIM3PIM2
SCHEMBL30929927 0.84 PLA2G2A (0.41) PIM1PIM3PIM2CSNK2A2CSNK2B
SCHEMBL21176409 0.84 PLA2G2A (0.41) PIM1PIM3PIM2CSNK2A2CSNK2B
SCHEMBL21185989 0.80 ALDH1A1 (0.42) ADORA3PIM1PIM3PIM2CSNK2A2
SCHEMBL19803010 0.77 ADORA3 (0.57) ADORA3TNKSCASP3SMN1; SMN2SENP7
SCHEMBL20967544 0.76 GAA (0.46) PIM1PIM3PIM2CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027613-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-01-26 US disclosed
US-20190229278-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027613-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NFE2L2, AOX1, CCNE2 ADORA3 4380/4885TNKS 4465/4885PIM1 3804/4885
US-20190229278-A1 Organic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device NFE2L2, AOX1, CCNE2 ADORA3 4380/4885TNKS 4465/4885PIM1 3804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.