Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | FPR1 | P21462 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187220 | 0.85 | FPR2 (0.38) | FPR2FPR1KDM1AMEN1KMT2A | |
| SCHEMBL21187147 | 0.82 | EPHX1 (0.45) | FPR2FPR1EPHX1ALDH1A1EPHX2 | |
| SCHEMBL21187146 | 0.79 | SMN1; SMN2 (0.41) | FPR2FPR1MEN1KMT2AALDH1A1 | |
| SCHEMBL21187132 | 0.73 | MAOA (0.48) | FPR2FPR1KMT2AEPHX1ALDH1A1 | |
| SCHEMBL21101398 | 0.72 | KDM1A (0.62) | KDM1AKMT2A | |
| SCHEMBL20347003 | 0.72 | KDM4E (0.46) | KDM1AKCNH2CHEK1 | |
| SCHEMBL21187130 | 0.72 | SMN1; SMN2 (0.39) | FPR2FPR1KDM1AMEN1KMT2A | |
| SCHEMBL21187199 | 0.69 | FPR1 (0.47) | FPR2FPR1MEN1KMT2AEPHX1 | |
| SCHEMBL21187195 | 0.68 | NPC1 (0.51) | MEN1KMT2AEPHX1ALDH1A1MAPT | |
| SCHEMBL21187119 | 0.68 | NPC1 (0.51) | MEN1KMT2AEPHX1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |