Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | FPR1 | P21462 | 7/20 | 0.39 |
| ▸ | FPR2 | P25090 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187136 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2AMEN1FPR1FPR2 | |
| SCHEMBL21187199 | 0.83 | FPR1 (0.47) | SMN1; SMN2KMT2AMEN1FPR1FPR2 | |
| SCHEMBL21187141 | 0.80 | FPR1 (0.52) | SMN1; SMN2KMT2AMEN1FPR1FPR2 | |
| SCHEMBL21187145 | 0.79 | FPR2 (0.39) | KMT2AMEN1FPR1FPR2ALDH1A1 | |
| SCHEMBL21187217 | 0.78 | MEN1 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1EPHX2 | |
| SCHEMBL21187125 | 0.78 | IDO1 (0.50) | SMN1; SMN2ALDH1A1EPHX2NPSR1CYP2C9 | |
| SCHEMBL21187113 | 0.76 | IDO1 (0.55) | SMN1; SMN2KMT2AMEN1FPR1FPR2 | |
| SCHEMBL21187085 | 0.76 | IDO1 (0.55) | SMN1; SMN2KMT2AMEN1FPR1FPR2 | |
| SCHEMBL21187116 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1EPHX2NPSR1CYP2C9 | |
| SCHEMBL21187132 | 0.76 | MAOA (0.48) | SMN1; SMN2KMT2AFPR1FPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |