SCHEMBL21189677

SCHEMBL21189677

CC(c1ccc(C2CCCCC2)cc1)(c1ccc(S)c(-c2ccccc2)c1)c1ccc(S)c(-c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 1/20 0.46
APP P05067 1/20 0.36
KIF11 P52732 1/20 0.36
ACE P12821 1/20 0.35
S1PR1 P21453 3/20 0.34
S1PR5 Q9H228 1/20 0.34
KMO O15229 1/20 0.34
PDK2 Q15119 1/20 0.34
DHODH Q02127 1/20 0.34
KMT2A Q03164 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22737899 0.94 CYP3A4 (0.42) CYP3A4CYP2C9APPKIF11ACE
SCHEMBL21189675 0.88 CYP3A4 (0.39) CYP3A4CYP2C9APPKIF11ACE
SCHEMBL23861381 0.85 CYP3A4 (0.48) CYP3A4CYP2C9APPKIF11ACE
SCHEMBL22737553 0.84 S1PR1 (0.42) CYP3A4CYP2C9KIF11ACES1PR1
SCHEMBL21189810 0.83 ESR1 (0.44) KIF11ALDH1A1ESR1ESR2
SCHEMBL21189626 0.82 ESR1 (0.47) CYP3A4KIF11ALDH1A1ESR1ESR2
SCHEMBL21189522 0.80 KIF11 (0.42) CYP2C9KIF11ESR1ESR2
SCHEMBL21189633 0.80 KIF11 (0.42) CYP2C9KIF11ESR1ESR2
SCHEMBL22738052 0.76 ESR2 (0.46) KIF11ADORA3ADORA2AADORA1ALDH1A1
SCHEMBL21189421 0.76 CYP3A4 (0.41) CYP3A4CYP2C9KIF11ACEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019142897-A1 COMPOUND, RESIN, COMPOSITION, AND PATTERN FORMING METHOD 三菱瓦斯化学株式会社 2019-07-25 WO disclosed