Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PPP5C | P53041 | 1/20 | 0.56 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407914 | 1.00 | PPM1B (0.56) | PPM1BKDM4EGMNNLMNATFPI2 | |
| SCHEMBL18873967 | 1.00 | PPM1B (0.56) | PPM1BKDM4EGMNNLMNATFPI2 | |
| SCHEMBL13556829 | 1.00 | PPM1B (0.56) | PPM1BKDM4EGMNNLMNATFPI2 | |
| SCHEMBL14381277 | 0.72 | TP53 (0.56) | PPM1BKDM4EGMNNLMNATFPI2 | |
| Demethyl-Cantharidin SCHEMBL19318920 | 0.72 | TP53 (1.00) | PPM1BKDM4EGMNNLMNATFPI2 | |
| Demethyl-Cantharidin SCHEMBL9675442 | 0.72 | TP53 (1.00) | PPM1BKDM4EGMNNLMNATFPI2 | |
| Demethyl-Cantharidin SCHEMBL3195020 | 0.72 | TP53 (1.00) | PPM1BKDM4EGMNNLMNATFPI2 | |
| SCHEMBL17773447 | 0.72 | TP53 (0.56) | PPM1BKDM4EGMNNLMNATFPI2 | |
| SCHEMBL2548229 | 0.72 | TP53 (0.56) | PPM1BKDM4EGMNNLMNATFPI2 | |
| Demethyl-Cantharidin SCHEMBL177729 | 0.72 | TP53 (1.00) | PPM1BKDM4EGMNNLMNATFPI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696686-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2020-06-30 | — | — | US | disclosed |
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2019-08-13 | — | — | US | disclosed |
| US-10301295-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-28 | — | — | US | disclosed |
| US-10206394-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-19 | — | — | US | disclosed |
| EP-3209133-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-03 | — | — | EP | disclosed |
| EP-3004063-B1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-07-18 | — | — | EP | disclosed |
| EP-3004052-B1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-04-18 | — | — | EP | disclosed |
| EP-3004043-B1 | HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF | SYNGENTA LTD (GB) | 2018-01-31 | — | — | EP | disclosed |
| US-20170320863-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-09 | — | — | US | disclosed |
| US-9808003-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | SYNGENTA LIMITED (GB) | 2017-11-07 | — | — | US | disclosed |
| EP-2185564-B1 | Herbicidally active cyclopentanedione compounds and derivatives thereof | SYNGENTA LTD (GB) | 2014-06-18 | — | — | EP | disclosed |
| US-8754242-B2 | Herbicides | SYNGENTA CROP PROTECTION LLC (US) | 2014-06-17 | — | — | US | disclosed |
| US-8530667-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| WO-2013079708-A1 | 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE COMPOUNDS, AND DERIVATIVES THEREOF | SYNGENTA LIMITED (GB) | 2013-06-06 | — | — | WO | disclosed |
| US-20120142529-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120094832-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2012-04-19 | — | — | US | disclosed |
| US-20100298140-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-11-25 | — | — | US | disclosed |
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2010-06-03 | — | — | US | disclosed |
| EP-2188294-A2 | TRICYCLIC BRIDGED CYCLOPENTANEDIONE DERIVATIVES AS HERBICIDES | Syngenta Limited (GB) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009030450-A2 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696686-B2 | Herbicidally active (alkynyl-phenyl)-substituted cyclic dione compounds and derivatives thereof | DDT, CNPY2, CNPY3 | PPM1B 952/4885KDM4E 406/4885GMNN 1687/4885 |
| US-20170320863-A1 | HERBICIDAL COMPOUNDS | DHRS9, DDT, MTX1 | PPM1B 832/4885KDM4E 1048/4885GMNN 622/4885 |
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | PPP1R10, TASP1, PPP5C | PPM1B 30/4885KDM4E 1897/4885GMNN 3844/4885 |
| US-10375956-B2 | Herbicidally active 2-(substituted-phenyl)-cyclopentane-1,3-dione compounds and derivatives thereof | DDT, HDHD5, CNPY2 | PPM1B 289/4885KDM4E 741/4885GMNN 963/4885 |
| US-20100298140-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | PPM1B 323/4885KDM4E 1070/4885GMNN 1348/4885 |
| US-10206394-B2 | Herbicidal compounds | GLRX3, DHRS9, DDT | PPM1B 759/4885KDM4E 1399/4885GMNN 424/4885 |
| US-20120142529-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | PPM1B 313/4885KDM4E 1092/4885GMNN 1351/4885 |
| US-20120094832-A1 | NOVEL HERBICIDES | DDT, CYP1B1, CYP1A1 | PPM1B 323/4885KDM4E 1070/4885GMNN 1348/4885 |
| US-10301295-B2 | Herbicidal compounds | DHRS9, DDT, MTX1 | PPM1B 832/4885KDM4E 1048/4885GMNN 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.