Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | PPM1B | O75688 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GMNN | O75496 | 3/20 | 0.56 |
| ▸ | TFPI2 | P48307 | 3/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | THPO | P40225 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.56 |
| ▸ | PPP5C | P53041 | 2/20 | 0.56 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14381277 | 1.00 | TP53 (0.56) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| SCHEMBL17773447 | 1.00 | TP53 (0.56) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| SCHEMBL13311452 | 1.00 | TP53 (0.56) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL19318920 | 0.72 | TP53 (1.00) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL9675442 | 0.72 | TP53 (1.00) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL3195020 | 0.72 | TP53 (1.00) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| SCHEMBL2120400 | 0.72 | PPM1B (0.56) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| Demethyl-Cantharidin SCHEMBL177729 | 0.72 | TP53 (1.00) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| SCHEMBL13556829 | 0.72 | PPM1B (0.56) | TP53PPM1BLMNASMN1; SMN2KDM4E | |
| SCHEMBL407914 | 0.72 | PPM1B (0.56) | TP53PPM1BLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2010-06-03 | — | — | US | claimed |
| EP-2086534-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | Genetic Technologies Limited (AU) | 2009-08-12 | — | — | EP | claimed |
| WO-2008058342-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2008-05-22 | — | — | WO | claimed |
| US-20240327448-A1 | LITHIUM REAGENTS AND THEIR USES IN SOLID PHASE SYNTHESIS | OLIX US, INC. | 2024-10-03 | — | — | US | disclosed |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2023-11-07 | — | — | US | disclosed |
| EP-3122757-B1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO LTD (CN) | 2023-09-06 | — | — | EP | disclosed |
| US-20220213053-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | ENYO PHARMA (FR) | 2022-07-07 | — | — | US | disclosed |
| US-11279683-B2 | Thiophene derivatives as antiviral agents | ENYO PHARMA (FR) | 2022-03-22 | — | — | US | disclosed |
| US-10696699-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-30 | — | — | US | disclosed |
| US-10696700-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-30 | — | — | US | disclosed |
| US-10683314-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-16 | — | — | US | disclosed |
| EP-1339716-B1 | LACTAM-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-11-03 | — | — | EP | disclosed |
| WO-2004009589-A1 | NOVEL 2,5-DISUBSTITUTED PYRIMIDINE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-01-29 | — | — | WO | disclosed |
| EP-1339716-A1 | NOVEL LACTAME-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1214325-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| EP-1214060-A2 | METHOD OF INHIBITING PROTEIN TYROSINE PHOSPHATASE 1B AND/OR T-CELL PROTEIN TYROSINE PHOSPHATASE AND/OR OTHER PTPASES WITH AN ASP RESIDUE AT POSITION 48 | NOVO NORDISK A/S (DK) | 2002-06-19 | — | — | EP | disclosed |
| WO-2002042299-A1 | NOVEL LACTAME-SUBSTITUTED PYRAZOLOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-30 | — | — | WO | disclosed |
| WO-2001019831-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPases) | NOVO NORDISK A/S (DK) | 2001-03-22 | — | — | WO | disclosed |
| WO-2001017516-A2 | METHOD OF INHIBITING PROTEIN TYROSINE PHOSPHATASE 1B AND/OR T-CELL PROTEIN TYROSINE PHOSPHATASE AND/OR OTHER PTPASES WITH AN ASP RESIDUE AT POSITION 48 | NOVO NORDISK A/S (DK) | 2001-03-15 | — | — | WO | disclosed |
| US-4057432-A | PHOTOGRAPHIC COUPLERS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696700-B2 | Charged linkers and their uses for conjugation | PHOSPHO1, PCTP, CD2BP2 | TP53 784/4885PPM1B 1261/4885LMNA 3457/4885 |
| US-20220213053-A1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS | MAVS, EIF2AK2, IRF3 | TP53 1353/4885PPM1B 738/4885LMNA 4815/4885 |
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | PPP1R10, TASP1, PPP5C | TP53 1847/4885PPM1B 30/4885LMNA 4332/4885 |
| US-20240327448-A1 | LITHIUM REAGENTS AND THEIR USES IN SOLID PHASE SYNTHESIS | POLRMT, NSUN2, RNGTT | TP53 1944/4885PPM1B 3970/4885LMNA 564/4885 |
| US-11279683-B2 | Thiophene derivatives as antiviral agents | MAVS, EIF2AK2, IRF3 | TP53 2656/4885PPM1B 786/4885LMNA 4796/4885 |
| US-10683314-B2 | Charged linkers and their uses for conjugation | PHOSPHO1, PCTP, CD2BP2 | TP53 784/4885PPM1B 1261/4885LMNA 3457/4885 |
| US-11807618-B2 | Thiophene derivatives as antiviral agents | MAVS, EIF2AK2, IRF3 | TP53 1353/4885PPM1B 738/4885LMNA 4815/4885 |
| US-10696699-B2 | Charged linkers and their uses for conjugation | PHOSPHO1, PCTP, CD2BP2 | TP53 784/4885PPM1B 1261/4885LMNA 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.