SCHEMBL2120697

SCHEMBL2120697

CCCC[Sn](CCCC)(OC(=O)c1ccccc1)O[Sn](CCCC)(CCCC)OC(=O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
CES2 O00748 4/20 0.44
CES1 P23141 4/20 0.44
TDP1 Q9NUW8 4/20 0.43
TSHR P16473 5/20 0.43
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
F2 P00734 1/20 0.41
NAAA Q02083 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
SLC6A3 Q01959 2/20 0.39
HTR1A P08908 1/20 0.39
CYP2D6 P10635 1/20 0.39
SCN1A P35498 1/20 0.39
SCN5A Q14524 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
MAPK1 P28482 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5498867 0.94 CES2 (0.46) LMNACES2CES1TDP1TSHR
SCHEMBL27954088 0.93 LMNA (0.51) LMNACES2CES1TDP1TSHR
SCHEMBL3093634 0.88 ALDH1A1 (0.48) LMNACES2CES1TDP1TSHR
Benzoic Acid SCHEMBL5496876 0.84 CES2 (0.39) LMNACES2CES1TSHRKMT2A
SCHEMBL409199 0.83 LMNA (0.51) LMNACES2CES1TDP1TSHR
SCHEMBL11132782 0.81 LMNA (0.49) LMNACES2CES1TDP1TSHR
SCHEMBL3092962 0.78 ALDH1A1 (0.48) LMNACES2CES1TDP1TSHR
SCHEMBL3093591 0.77 CES2 (0.51) LMNACES2CES1NAAA
SCHEMBL3098844 0.76 ELANE (0.50) LMNAKMT2AMEN1L3MBTL1MAPK1
SCHEMBL1525821 0.74 LMNA (0.47) LMNATDP1TSHRKMT2ASLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111100168-A Method for reducing acid value of synthesized sucrose-6-acetate solution 广东广业清怡食品科技有限公司 2020-05-05 CN claimed
US-8927706-B2 Based-assisted formation of tin-sucrose adducts Tate & Lyle Technology, Ltd. (GB) 2015-01-06 US claimed
US-8796446-B2 Extraction of carboxylic acids with tin compounds TATE & LYLE TECHNOLOGY LIMITED (GB) 2014-08-05 US claimed
WO-2012153128-A1 EXTRACTION OF CARBOXYLIC ACIDS WITH TIN COMPOUNDS TATE & LYLE TECHNOLOGY LIMITED (GB) 2012-11-15 WO claimed
US-20120289693-A1 Extraction of Carboxylic Acids with Tin Compounds TATE & LYLE TECHNOLOGY LIMITED (GB) 2012-11-15 US claimed
US-20120095199-A1 Based-Assisted formation of Tin-Sucrose Adducts TATE & LYLE TECHNOLOGY LTD. (GB) 2012-04-19 US claimed
WO-2010114683-A1 BASE-ASSISTED FORMATION OF TIN-SOCROSE ADDUCTS TATE & LYLE TECHNOLOGY LTD (GB) 2010-10-07 WO claimed
US-20090076261-A1 Novel process for preparing sucrose-6-esters POLYMED THERAPEUTICS, INC. (US) 2009-03-19 US claimed
EP-0776903-B1 Process for the production of sucrose-6-ester. MCNEIL PPC INC (US) 2003-01-29 EP claimed
EP-0776903-A1 Improved sucrose-6-ester process McNEIL-PPC, INC. (US) 1997-06-04 EP claimed
US-5470969-A Catalyzed sucrose-6-ester process MCNEIL-PPC, INC. (US) 1995-11-28 US claimed
EP-0475619-B1 Catalyzed sucrose-6-ester process MCNEIL PPC INC (US) 1995-10-11 EP claimed
EP-0509437-B1 Electrocoating composition KANSAI PAINT CO LTD (JP) 1995-01-25 EP claimed
US-5330839-A Electrocoating composition containing blocked isocyanate, dialkyltin aromatic carboxylate and a bismuth or zirconium compound KANSAI PAINT CO., LTD. (JP) 1994-07-19 US claimed
EP-0509437-A1 Electrocoating composition KANSAI PAINT CO., LTD. (JP) 1992-10-21 EP claimed
EP-0475619-A1 Catalyzed sucrose-6-ester process McNEIL-PPC, INC. (US) 1992-03-18 EP claimed
CN-111100168-A Method for reducing acid value of synthesized sucrose-6-acetate solution 广东广业清怡食品科技有限公司 2020-05-05 CN disclosed
US-20090076261-A1 Novel process for preparing sucrose-6-esters POLYMED THERAPEUTICS, INC. (US) 2009-03-19 US disclosed
EP-0509437-A1 Electrocoating composition KANSAI PAINT CO., LTD. (JP) 1992-10-21 EP disclosed
US-4038304-A URETHANE PREPOLYMER TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120289693-A1 Extraction of Carboxylic Acids with Tin Compounds SI, SUCNR1, NISCH LMNA 4642/4885CES2 771/4885CES1 451/4885
US-20090076261-A1 Novel process for preparing sucrose-6-esters SI, TREH, DDOST LMNA 4655/4885CES2 752/4885CES1 212/4885
US-20120095199-A1 Based-Assisted formation of Tin-Sucrose Adducts TST, AS3MT, NAT10 LMNA 4207/4885CES2 934/4885CES1 2325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.