Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379213 | 1.00 | HCAR2 (0.42) | HCAR2KEAP1NFE2L2ATM | |
| SCHEMBL1203690 | 0.88 | HCAR2 (0.52) | HCAR2KEAP1NFE2L2ATM | |
| SCHEMBL9245442 | 0.86 | KEAP1 (0.33) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL1695499 | 0.82 | — | — | |
| SCHEMBL1695500 | 0.82 | — | — | |
| SCHEMBL2043030 | 0.79 | — | — | |
| SCHEMBL13390888 | 0.76 | — | — | |
| SCHEMBL13657268 | 0.74 | ALDH1A1 (0.48) | — | |
| SCHEMBL6129816 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL584332 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947808-B | Preparation method of stannous octoate | 盘锦洪鼎化工有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-101312973-B | Indolizine derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI-AVENTIS (FR) | 2011-12-28 | — | — | CN | claimed |
| CN-101312973-A | Indolizine derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI AVENTIS (FR) | 2008-11-26 | — | — | CN | claimed |
| WO-2006020663-A2 | AEROBIC SUCCINATE PRODUCTION IN BACTERIA | RICE UNIVERSITY (US) | 2006-02-23 | — | — | WO | claimed |
| US-20060040368-A1 | Aerobic succinate production in bacteria | NATIONAL SCIENCE FOUNDATION | 2006-02-23 | — | — | US | claimed |
| CN-1602868-A | Dripping pills of ketotifen fumarate and its preparation method | NANCHANG HELIOEAST SCIENCE & TECHNOLOGY CO LTD (CN) | 2005-04-06 | — | — | CN | claimed |
| WO-2023196399-A1 | LIPID NANOPARTICLES AND POLYNUCLEOTIDES ENCODING ARGININOSUCCINATE LYASE FOR THE TREATMENT OF ARGININOSUCCINIC ACIDURIA | MODERNATX, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| EP-3911624-A1 | SYNTHESIS OF ORGANIC ACIDS FROM ALPHA-KETO ACIDS | Furman University (US) | 2021-11-24 | — | — | EP | disclosed |
| CN-108947808-B | Preparation method of stannous octoate | 盘锦洪鼎化工有限公司 | 2021-09-28 | — | — | CN | disclosed |
| US-11008305-B2 | DNA-PK inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2021-05-18 | — | — | US | disclosed |
| WO-2020150568-A1 | SYNTHESIS OF ORGANIC ACIDS FROM ALPHA-KETO ACIDS | FURMAN UNIVERSITY (US) | 2020-07-23 | — | — | WO | disclosed |
| US-20200231527-A1 | SYNTHESIS OF ORGANIC ACIDS FROM ALPHA-KETO ACIDS | FURMAN UNIVERSITY | 2020-07-23 | — | — | US | disclosed |
| US-20200062732-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED | 2020-02-27 | — | — | US | disclosed |
| CN-1602868-A | Dripping pills of ketotifen fumarate and its preparation method | NANCHANG HELIOEAST SCIENCE & TECHNOLOGY CO LTD (CN) | 2005-04-06 | — | — | CN | disclosed |
| CN-1381456-A | Pyrimidine-4-keto compound, its preparation method and medicine composition containing them | SIRVIR LAB (FR) | 2002-11-27 | — | — | CN | disclosed |
| CN-1087934-C | Use of phenalkylamines | HOFFMANN LA ROCHE (CH) | 2002-07-24 | — | — | CN | disclosed |
| CN-1103781-A | Use of phenalkylamines | HOFFMANN LA ROCHE (CH) | 1995-06-21 | — | — | CN | disclosed |
| CN-1017706-B | Process for preparing 1, 5-benzothiazepine derivatives | TANABE SEIYAKU CO (JP) | 1992-08-05 | — | — | CN | disclosed |
| CN-1017151-B | PROCESSES FOR PREPARING NAPHTHOTHIAZEPINE DERIVATIVE | TANABE SEIYAKU CO (JP) | 1992-06-24 | — | — | CN | disclosed |
| CN-85103524-A | Process for preparing 1, 5-benzothiazine derivatives | — | 1986-11-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200231527-A1 | SYNTHESIS OF ORGANIC ACIDS FROM ALPHA-KETO ACIDS | HOGA1, BCKDK, PCCA | HCAR2 340/4885KEAP1 2252/4885NFE2L2 2484/4885 |
| US-11008305-B2 | DNA-PK inhibitors | POLK, DTYMK, DCK | HCAR2 3919/4885KEAP1 1279/4885NFE2L2 3337/4885 |
| US-20200062732-A1 | DNA-PK INHIBITORS | POLK, DTYMK, DCK | HCAR2 3919/4885KEAP1 1279/4885NFE2L2 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.