Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22623985 | 0.81 | GRIN2D (0.43) | ALDH1A1 | |
| SCHEMBL22984969 | 0.72 | NPSR1 (0.41) | NPSR1KMT2ALMNA | |
| SCHEMBL25698481 | 0.71 | NOS3 (0.40) | — | |
| SCHEMBL31728345 | 0.71 | NPSR1 (0.41) | NPSR1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL28710684 | 0.71 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL14888179 | 0.71 | NCF1 (0.39) | NPSR1 | |
| SCHEMBL21946383 | 0.71 | NPSR1 (0.35) | NPSR1KMT2ALMNA | |
| SCHEMBL13563553 | 0.70 | TRPA1 (0.44) | — | |
| SCHEMBL14930168 | 0.70 | PRMT6 (0.50) | CARM1PRMT6CCR3PRMT3PRMT1 | |
| Hydrochloric Acid SCHEMBL14311891 | 0.69 | NCF1 (0.38) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743430-B1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2019147782-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-08-01 | — | — | WO | disclosed |