Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107859 | 0.73 | ALDH1A1 (0.38) | HPGD | |
| SCHEMBL23370334 | 0.73 | KDM4E (0.30) | HPGD | |
| SCHEMBL21230340 | 0.72 | HPGD (0.32) | HPGDHSD17B10 | |
| SCHEMBL25647631 | 0.67 | MEN1 (0.33) | — | |
| SCHEMBL21230395 | 0.64 | ACHE (0.36) | HPGDHSD17B10 | |
| SCHEMBL21559977 | 0.64 | GABRA1 (0.43) | HPGD | |
| SCHEMBL25669516 | 0.64 | ALDH1A1 (0.33) | HPGDHSD17B10 | |
| SCHEMBL13661685 | 0.64 | RAPGEF4 (0.36) | HPGD | |
| SCHEMBL25669677 | 0.62 | GRIN2D (0.33) | HPGD | |
| SCHEMBL11311046 | 0.62 | ALOX15 (0.41) | HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019150305-A1 | SUBSTITUTED QUINAZOLINE AND PYRIDOPYRIMIDINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. (US) | 2019-08-08 | — | — | WO | disclosed |