Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210464 | 0.89 | MAPT (0.41) | FOLH1MAPTRAB9A | |
| SCHEMBL212596 | 0.85 | MAOB (0.35) | MAOBFOLH1LMNAMAPTRAB9A | |
| SCHEMBL211523 | 0.85 | CTSK (0.38) | MAOBFOLH1RAB9AKDM4EP2RX7 | |
| SCHEMBL2840754 | 0.85 | CTSK (0.38) | MAOBFOLH1RAB9AKDM4EP2RX7 | |
| SCHEMBL210987 | 0.82 | FOLH1 (0.36) | MAOBFOLH1LMNAMAPTRAB9A | |
| SCHEMBL212050 | 0.81 | ABL1 (0.38) | RAB9ACTSK | |
| SCHEMBL212323 | 0.81 | MAPT (0.40) | FOLH1MAPTRAB9A | |
| SCHEMBL2726698 | 0.79 | SCD5 (0.35) | MAOBLMNAMAPTRAB9AL3MBTL1 | |
| SCHEMBL212861 | 0.78 | KDM4E (0.38) | MAOBFOLH1LMNAMAPTRAB9A | |
| SCHEMBL2724049 | 0.78 | SCD5 (0.34) | MAOBFOLH1LMNAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |