Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241499 | 0.82 | LMNA (0.46) | ADORA2AADORA1ESR2PTGS1CNR1 | |
| SCHEMBL21241236 | 0.79 | MKNK1 (0.35) | PTGS2 | |
| SCHEMBL21241175 | 0.78 | PDE4B (0.43) | ADORA2AADORA1PDE4DPDE4BNPC1 | |
| SCHEMBL21241087 | 0.78 | TRPA1 (0.41) | ESR2PTGS2PTGS1MAOBIDO1 | |
| SCHEMBL21241363 | 0.74 | ADORA2A (0.45) | ADORA2AADORA1PTGS2PTGS1TP53 | |
| SCHEMBL21241364 | 0.73 | SDHB (0.39) | ALOX5ADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL21241521 | 0.70 | ALDH1A1 (0.49) | ADORA2AADORA1PTGS1NPC1NFKB1 | |
| SCHEMBL22598437 | 0.70 | KIF11 (0.45) | MAOBTRPA1 | |
| SCHEMBL16068089 | 0.67 | PIK3CD (0.47) | ALOX5PTGS2PTGS1 | |
| SCHEMBL15658105 | 0.67 | PDE4D (0.49) | PTGS2PTGS1PDE4DCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019149260-A1 | PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2019-08-08 | — | — | WO | disclosed |