Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241844 | 0.85 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KMT2APOLBNPC1 | |
| SCHEMBL20979707 | 0.83 | ALDH1A1 (0.54) | KDM4ESMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL21242060 | 0.80 | F2R (0.50) | KDM4ESMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL1840451 | 0.79 | KDM4E (0.60) | KDM4ESMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL20826224 | 0.78 | HSD17B10 (0.63) | KDM4EHPGDALDH1A1KMT2APOLB | |
| SCHEMBL21241848 | 0.77 | ADORA3 (0.44) | KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL1285808 | 0.75 | NPC1 (0.63) | KDM4ESMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL609165 | 0.75 | ATM (0.57) | KDM4ESMN1; SMN2HPGDALDH1A1CTSL | |
| SCHEMBL29417854 | 0.75 | NPC1 (0.63) | KDM4ESMN1; SMN2HPGDALDH1A1KMT2A | |
| SCHEMBL29780425 | 0.75 | KDM4E (0.56) | KDM4ESMN1; SMN2HPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |