Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241931 | 0.83 | MAPT (0.55) | KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL21242060 | 0.81 | F2R (0.50) | L3MBTL1KMT2AMEN1 | |
| SCHEMBL21224247 | 0.81 | MEN1 (0.56) | ADORA3L3MBTL1KMT2ANPC1RAB9A | |
| SCHEMBL21241854 | 0.78 | MAPT (0.48) | KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL21241801 | 0.77 | KDM4E (0.50) | KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL21242061 | 0.76 | POLB (0.52) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL21241981 | 0.76 | ADORA3 (0.54) | ADORA3L3MBTL1KMT2AMEN1 | |
| SCHEMBL21241844 | 0.71 | SMN1; SMN2 (0.46) | L3MBTL1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL21224272 | 0.70 | CNR1 (0.55) | ADORA3KMT2AADORA2AADORA1ADORA2B | |
| SCHEMBL20979707 | 0.70 | ALDH1A1 (0.54) | KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019152437-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2019-08-08 | — | — | WO | disclosed |