Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2124453

C=C(C)C(=O)NC(CC)[N+](C)(C)CC(=O)OC.[Cl-]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.36
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5332071 0.88 MGAM (0.39) TGFBR1
SCHEMBL9451823 0.80 TGFBR1 (0.42) TGFBR1RXFP1
Fluoride Ion SCHEMBL8934072 0.79 TGFBR1 (0.41) TGFBR1RXFP1
Hydrochloric Acid SCHEMBL4764541 0.79 TGFBR1 (0.43) TGFBR1
Hydrochloric Acid SCHEMBL61003 0.79 TGFBR1 (0.43) TGFBR1
Hydrochloric Acid SCHEMBL4920381 0.77 TGFBR1 (0.42) TGFBR1
SCHEMBL33606 0.77 TGFBR1 (0.44) TGFBR1RXFP1
SCHEMBL12027706 0.77 TGFBR1 (0.34) TGFBR1
Hydrochloric Acid SCHEMBL10425311 0.76 TGFBR1 (0.39) TGFBR1RXFP1
Hydrochloric Acid SCHEMBL10337216 0.76 TGFBR1 (0.42) TGFBR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539676-B1 MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM SOLVAY USA INC (US) 2017-07-26 EP disclosed
US-20160287509-A1 Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant PROCTER & GAMBLE (US) 2016-10-06 US disclosed
US-9427391-B2 Personal care compositions containing cationic synthetic copolymer and a detersive surfactant THE PROCTER & GAMBLE COMPANY (US) 2016-08-30 US disclosed
EP-2644592-A1 Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom RHODIA INC. (US) 2013-10-02 EP disclosed
EP-2442787-A2 PERSONAL CARE COMPOSITION COMPRISING A SYNTHETIC CATIONIC POLYMER The Procter & Gamble Company (US) 2012-04-25 EP disclosed
US-20100322878-A1 Personal Care Composition Comprising a Synthetic Cationic Polymer THE PROCTER & GAMBLE COMPANY 2010-12-23 US disclosed
WO-2010148220-A2 PERSONAL CARE COMPOSITION COMPRISING A SYNTHETIC CATIONIC POLYMER THE PROCTER & GAMBLE COMPANY (US) 2010-12-23 WO disclosed
WO-2010080167-A2 PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SYNTHETIC COPOLYMER AND A DETERSIVE SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 2010-07-15 WO disclosed
WO-2009117569-A2 PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SYNTHETIC COPOLYMER AND A DETERSIVE SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 2009-09-24 WO disclosed
US-20090176675-A1 Personal Care Compositions Containing Cationically Modified Starch and an Anionic Surfactant System THE PROCTER & GAMBLE COMPANY 2009-07-09 US disclosed
US-20080206179-A1 Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant PROCTER & GAMBLE COMPANY, THE 2008-08-28 US disclosed
US-20070207109-A1 Personal care compositions containing cationic synthetic copolymer and a detersive surfactant PROCTER & GAMBLE COMPANY, THE 2007-09-06 US disclosed
US-7247693-B2 Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom RHODIA INC. (US) 2007-07-24 US disclosed
WO-2007080538-A2 PERSONAL CARE COMPOSITIONS CONTAINING CATIONIC SYNTHETIC COPOLYMER AND A DETERSIVE SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 2007-07-19 WO disclosed
EP-1539676-A4 MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM RHODIA (US) 2007-02-21 EP disclosed
US-20060111533-A1 Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom RHODIA OPERATIONS (FR) 2006-05-25 US disclosed
US-7030275-B2 Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom RHODIA INC. (US) 2006-04-18 US disclosed
EP-1539676-A1 MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM Rhodia Inc. (US) 2005-06-15 EP disclosed
US-20040010106-A1 Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom RHODIA OPERATIONS (FR) 2004-01-15 US disclosed
WO-2003101935-A1 MONOMER COMPOUND COMPRISING SEVERAL CATIONIC GROUPS, PROCESS FOR MAKING THE SAME, AND POLYMERS COMPRISING UNITS DERIVING THEREFROM RHODIA INC. (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100322878-A1 Personal Care Composition Comprising a Synthetic Cationic Polymer PARN, PARG, PUF60 TGFBR1 3375/4885RXFP1 3830/4885
US-20090176675-A1 Personal Care Compositions Containing Cationically Modified Starch and an Anionic Surfactant System CUTA, SCLY, MC1R TGFBR1 3531/4885RXFP1 4396/4885
US-20080206179-A1 Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant C5, C3AR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 TGFBR1 676/4885RXFP1 1989/4885
US-20160287509-A1 Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CFH, C9 TGFBR1 1451/4885RXFP1 1951/4885
US-20070207109-A1 Personal care compositions containing cationic synthetic copolymer and a detersive surfactant H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CFH, C9 TGFBR1 1451/4885RXFP1 1951/4885
US-20040010106-A1 Monomer compound comprising several cationic groups, process for making the same, and polymers comprising units deriving therefrom PCNA, PBRM1, B2M TGFBR1 925/4885RXFP1 1492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.