SCHEMBL212537

SCHEMBL212537

CC(C)(C)OCOCOC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13411447 0.87 ALDH1A1 (0.32) MAPK1ALDH1A1
SCHEMBL9972441 0.85
SCHEMBL6176534 0.84 MAPK1 (0.40) MAPK1ALDH1A1TSHRTDP1
SCHEMBL6175846 0.83
SCHEMBL14182576 0.83
SCHEMBL7424817 0.83
SCHEMBL7424822 0.83 MAPK1 (0.33) MAPK1
SCHEMBL8187296 0.81
SCHEMBL12744839 0.81 CYP2C19 (0.32) MAPK1
SCHEMBL13126000 0.81 MAPK1 (0.31) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1011 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230049294-A1 STEREOSELECTIVE PROCESS OF MANUFACTURE OF PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-02-16 US claimed
WO-2021216722-A1 STEREOSELECTIVE PROCESS OF MANUFACTURE OF PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2021-10-28 WO claimed
US-10570088-B2 Blood brain barrier-penetrating oximes for cholinesterase reactivation HUMAN BIOMOLECULAR RES FOUNDATION (US) 2020-02-25 US claimed
US-20170349538-A1 Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation Human BioMolecular Research Foundation (US) 2017-12-07 US claimed
US-8921599-B2 Processes for forming amide bonds and compositions related thereto EMORY UNIVERSITY (US) 2014-12-30 US claimed
US-20140051712-A1 BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION HUMAN BIOMOLECULAR RESEARCH INSTITUTE 2014-02-20 US claimed
EP-1979362-B1 NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA COMMISSARIAT ENERGIE ATOMIQUE (FR) 2010-12-15 EP claimed
US-20090005269-A1 Novel Silane Compounds and Their Use in Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-01-01 US claimed
EP-0600161-A1 Amino acid terminated polyesters having predetermined monomeric sequence United States Surgical Corporation (US) 1994-06-08 EP claimed
EP-0579173-A2 Polyesters having predeterminated monomeric sequence United States Surgical Corporation (US) 1994-01-19 EP claimed
US-5256762-A Polyesters having predetermined monomeric sequence UNITED STATES SURGICAL CORPORATION (US) 1993-10-26 US claimed
US-5248761-A Amino acid terminated polyesters having predetermined monomeric sequence UNITED STATES SURGICAL CORPORATION (US) 1993-09-28 US claimed
EP-3494996-B1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 158P1D7 PROTEINS AGENSYS INC (US) 2026-04-15 EP disclosed
US-12551499-B2 Highly active compounds against COVID-19 Atea Pharmaceuticals, Inc. (US) 2026-02-17 US disclosed
US-20260034234-A1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS AGENSYS, INC. (US) 2026-02-05 US disclosed
US-20260000604-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-191P4D12 ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOF AGENSYS, INC. (US) 2026-01-01 US disclosed
US-5256762-A Polyesters having predetermined monomeric sequence UNITED STATES SURGICAL CORPORATION (US) 1993-10-26 US disclosed
US-5248761-A Amino acid terminated polyesters having predetermined monomeric sequence UNITED STATES SURGICAL CORPORATION (US) 1993-09-28 US disclosed
US-4792560-A ANTIALLERGENS; ANTIINFLAMMATORY AGENTS RORER PHARMACEUTICAL CORPORATION (US) 1988-12-20 US disclosed
EP-0196674-A2 Hydroxamates as modulators of arachidonic acid metabolic pathways USV PHARMACEUTICAL CORPORATION (US) 1986-10-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005269-A1 Novel Silane Compounds and Their Use in Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports SELE, ELANE, EPCAM MAPK1 4013/4885ALDH1A1 374/4885TSHR 3246/4885
US-20260000604-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-191P4D12 ANTIBODY DRUG CONJUGATES AND METHODS OF USE THEREOF CD44, CA12, H1-10 MAPK1 4480/4885ALDH1A1 3280/4885TSHR 2385/4885
US-10570088-B2 Blood brain barrier-penetrating oximes for cholinesterase reactivation ACHE, BCHE, PYGB MAPK1 3478/4885ALDH1A1 1236/4885TSHR 2012/4885
US-20140051712-A1 BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION BCHE, ACHE, PYGB MAPK1 3260/4885ALDH1A1 1908/4885TSHR 2320/4885
US-12551499-B2 Highly active compounds against COVID-19 PNP, SLC29A2, MTAP MAPK1 2672/4885ALDH1A1 1808/4885TSHR 3265/4885
US-20230049294-A1 STEREOSELECTIVE PROCESS OF MANUFACTURE OF PURINE PHOSPHORAMIDATES NUDT1, PNP, ITPA MAPK1 790/4885ALDH1A1 1210/4885TSHR 3591/4885
US-20260034234-A1 ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS IGSF11, ARID2, DYNLL2 MAPK1 4705/4885ALDH1A1 1803/4885TSHR 3069/4885
US-20170349538-A1 Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation ACHE, BCHE, PYGB MAPK1 3478/4885ALDH1A1 1236/4885TSHR 2012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.