SCHEMBL2127629

SCHEMBL2127629

CC(C)(C)C(OOC(c1ccccc1)C(C)(C)C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
RIPK1 Q13546 2/20 0.39
SLC6A4 P31645 3/20 0.38
SLC6A3 Q01959 3/20 0.38
SLC6A2 P23975 2/20 0.38
MAPK1 P28482 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
AOC3 Q16853 1/20 0.36
CACNA1F O60840 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
ADRA2B P18089 1/20 0.36
CHRM3 P20309 1/20 0.36
ADRA1A P35348 1/20 0.36
HRH1 P35367 1/20 0.36
OPRK1 P41145 1/20 0.36
CACNA1D Q01668 1/20 0.36
KCNH2 Q12809 1/20 0.36
CACNA1S Q13698 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7438325 0.85 ATM (0.41) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL12344306 0.83 ATM (0.40) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL11911981 0.83 ATM (0.40) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL14663964 0.83 ATM (0.40) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL7701248 0.81 ATM (0.39) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL11786688 0.81 ATM (0.43) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL705886 0.81 ATM (0.39) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL129959 0.79 ATM (0.38) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL21725633 0.79 RIPK1 (0.39) ATML3MBTL1RIPK1SLC6A4SLC6A3
SCHEMBL1826870 0.78 ALDH1A1 (0.37) ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207273-B2 Block copolymers useful as tensioning agents RHODIA CHIMIE (FR) 2012-06-26 US disclosed
EP-1858940-B1 NON COSMETIC COMPOSITION COMPRISING A BLOCK COPOLYMER USEFUL AS TENSIONER RHODIA CHIMIE SA (FR) 2012-04-25 EP disclosed
EP-2113003-B1 DIBLOCK COPOPLYMER INCLUDING UNITS DERIVED FROM STYRENE AND UNITS DERIVED FROM ACRYLIC ACID RHODIA OPERATIONS (FR) 2011-12-21 EP disclosed
US-20100113666-A1 DIBLOCK COPOLYMER INCLUDING UNITS DERIVED FROM STYRENE AND UNITS DERIVED FROM ACRYLIC ACID RHODIA SERVICES (FR) 2010-05-06 US disclosed
EP-2113003-A1 DIBLOCK COPOPLYMER INCLUDING UNITS DERIVED FROM STYRENE AND UNITS DERIVED FROM ACRYLIC ACID Rhodia Opérations (FR) 2009-11-04 EP disclosed
US-20090269299-A1 Cosmetic Method for use in Smoothing the Skin L'OREAL (FR) 2009-10-29 US disclosed
US-20090221756-A1 Block Copolymers Useful as Tensioning Agents RHODIA CHIMIE (FR) 2009-09-03 US disclosed
EP-1951377-B1 COSMETIC METHOD FOR USE IN SMOOTHING THE SKIN OREAL (FR) 2009-06-03 EP disclosed
EP-1865918-B1 COSMETIC USE OF A PARTICULAR COPOLYMER AS SKIN TENSOR IN A COSMETIC COMPOSITION OREAL (FR) 2009-05-06 EP disclosed
US-20080233077-A1 Cosmetic Use of a Particular Copolymer as Skin Tensor in a Cosmetic Composition L'OREAL (FR) 2008-09-25 US disclosed
WO-2008090063-A1 DIBLOCK COPOPLYMER INCLUDING UNITS DERIVED FROM STYRENE AND UNITS DERIVED FROM ACRYLIC ACID RHODIA OPERATIONS (FR) 2008-07-31 WO disclosed
WO-2008087211-A1 O/W EMULSION WITH BLOCK POLYMERS L'OREAL (FR) 2008-07-24 WO disclosed
WO-2008086928-A1 O/W COSMETIC EMULSION COMPRISING A LIPOPHILIC UV SCREENING AGENT, A POLAR OIL AND A POLYSTYRENE-BLOCK-POLY(ACRYLIC ACID-STAT-C1-C4 ALKYL ACRYLATE) DIBLOCK COPOLYMER L'OREAL (FR) 2008-07-24 WO disclosed
WO-2008087212-A1 EMULSION STABILIZED WITH BLOCK POLYMERS L'OREAL (FR) 2008-07-24 WO disclosed
WO-2008087119-A1 COSMETIC COMPOSITION COMPRISING A DIBLOCK COPOLYMER L'OREAL (FR) 2008-07-24 WO disclosed
EP-1865918-A1 COSMETIC USE OF A PARTICULAR COPOLYMER AS SKIN TENSOR IN A COSMETIC COMPOSITION L'Oréal (FR) 2007-12-19 EP disclosed
EP-1858940-A1 BLOCK COPOLYMER USEFUL AS TENSOR RHODIA CHIMIE (FR) 2007-11-28 EP disclosed
WO-2006097641-A1 BLOCK COPOLYMER USEFUL AS TENSOR RHODIA CHIMIE (FR) 2006-09-21 WO disclosed
WO-2006097529-A1 COSMETIC USE OF A PARTICULAR COPOLYMER AS SKIN TENSOR IN A COSMETIC COMPOSITION L'OREAL (FR) 2006-09-21 WO disclosed
US-4006194-A Production of phenols THE LUMMUS COMPANY (US) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090269299-A1 Cosmetic Method for use in Smoothing the Skin CUTA, GLA, DSG1 ATM 1870/4885L3MBTL1 4067/4885RIPK1 3845/4885
US-20080233077-A1 Cosmetic Use of a Particular Copolymer as Skin Tensor in a Cosmetic Composition CUTA, MATR3, MSH6 ATM 167/4885L3MBTL1 2803/4885RIPK1 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.