Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213604 | 0.78 | CTSK (0.57) | CTSKNOTUMKDM4EKMT2AL3MBTL1 | |
| SCHEMBL2841496 | 0.73 | CTSK (0.36) | CTSKNOTUMMTORABL1RAB9A | |
| SCHEMBL2837600 | 0.73 | CTSK (0.52) | CTSKNOTUMKDM4EMTORABL1 | |
| SCHEMBL215045 | 0.72 | NOTUM (0.49) | CTSKNOTUMKDM4EMTORABL1 | |
| SCHEMBL2839420 | 0.71 | CTSK (0.38) | CTSKNOTUMMTORABL1 | |
| SCHEMBL213202 | 0.70 | NOTUM (0.46) | CTSKNOTUMKDM4EMTORABL1 | |
| SCHEMBL212870 | 0.70 | NOTUM (0.46) | CTSKNOTUMKDM4EMTORABL1 | |
| SCHEMBL2574304 | 0.69 | EPHX1 (0.61) | CTSKNOTUMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22550360 | 0.69 | CTSK (0.50) | CTSKNOTUMKDM4EMTORABL1 | |
| SCHEMBL2837602 | 0.69 | NOTUM (0.46) | CTSKNOTUMKDM4EMTORABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |