Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | QDPR | P09417 | 3/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21288986 | 0.77 | APP (0.42) | APPALOX5CYP3A4ALOX15HSD17B10 | |
| SCHEMBL23315174 | 0.77 | — | — | |
| SCHEMBL18388071 | 0.73 | MEN1 (0.30) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL9926565 | 0.72 | ALDH1A1 (0.38) | CYP3A4HSD17B10ESR1ALDH1A1ESR2 | |
| SCHEMBL18820407 | 0.71 | — | — | |
| SCHEMBL18308730 | 0.71 | ALDH1A1 (0.41) | CYP3A4HSD17B1HSD17B2ALDH1A1HPGD | |
| SCHEMBL21289083 | 0.71 | ALOX5 (0.41) | APPALOX5HSD17B10HSD17B1ESR1 | |
| SCHEMBL18411506 | 0.71 | — | — | |
| SCHEMBL19824460 | 0.71 | KIF11 (0.35) | CYP3A4HSD17B10HSD17B1HSD17B2ESR1 | |
| SCHEMBL18308759 | 0.71 | ALDH1A1 (0.41) | CYP3A4HSD17B1HSD17B2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2022-01-18 | — | — | US | disclosed |
| US-20210139781-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2021-05-13 | — | — | US | disclosed |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | APP 1164/4885ALOX5 1504/4885CYP3A4 1699/4885 |
| US-11225606-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | VCL, PLEC, EML4 | APP 799/4885ALOX5 2243/4885CYP3A4 2115/4885 |
| US-20190256777-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, PLEC, EML4 | APP 799/4885ALOX5 2243/4885CYP3A4 2115/4885 |
| US-20210139781-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, ILK, LCP1 | APP 1164/4885ALOX5 1504/4885CYP3A4 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.