Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047000 | 0.90 | AKR1C3 (0.55) | AKR1C3HCAR3ALOX15L3MBTL1MAPT | |
| SCHEMBL29799202 | 0.89 | CYP19A1 (0.45) | NPC1RAB9ATDP1AKR1C3ALOX15 | |
| SCHEMBL21296982 | 0.89 | CYP19A1 (0.45) | NPC1RAB9ATDP1AKR1C3ALOX15 | |
| SCHEMBL21296984 | 0.86 | AKR1C3 (0.49) | AKR1C3HCAR3ALOX15L3MBTL1MAPT | |
| SCHEMBL22815682 | 0.83 | AKR1C3 (0.47) | AKR1C3HCAR3ALOX15L3MBTL1MAPT | |
| SCHEMBL29891535 | 0.83 | AKR1C3 (0.47) | AKR1C3HCAR3ALOX15L3MBTL1MAPT | |
| SCHEMBL22816536 | 0.82 | AKR1C3 (0.47) | AKR1C3HCAR3ALOX15L3MBTL1MAPT | |
| SCHEMBL22815906 | 0.82 | ALOX15 (0.47) | AKR1C3ALOX15L3MBTL1MAPTPOLB | |
| SCHEMBL21296968 | 0.82 | AKR1C3 (0.46) | AKR1C3HCAR3ALOX15L3MBTL1MAPT | |
| SCHEMBL21296920 | 0.81 | NPBWR1 (0.51) | AKR1C3ALOX15L3MBTL1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2019165159-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | NPC1 1529/4885RAB9A 2533/4885TDP1 1110/4885 |
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | XDH, PNPO, LOX | NPC1 1529/4885RAB9A 2533/4885TDP1 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.