SCHEMBL21297741

SCHEMBL21297741

Cc1c(C)c2nccnc2c2ncccc12

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.83
HSP90AA1 P07900 2/20 0.83
NPC1 O15118 1/20 0.83
CCR1 P32246 6/20 0.50
CCR8 P51685 6/20 0.50
HTT P42858 2/20 0.46
PSMD14 O00487 1/20 0.46
COPS5 Q92905 1/20 0.46
SLC6A2 P23975 1/20 0.46
CCR5 P51681 4/20 0.44
KDM4E B2RXH2 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 3/20 0.39
GMNN O75496 1/20 0.39
TP53 P04637 1/20 0.39
MMP2 P08253 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250356 0.91 L3MBTL1 (1.00) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL21297746 0.89 L3MBTL1 (0.71) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL30753478 0.89 L3MBTL1 (0.95) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL28307634 0.89 L3MBTL1 (0.95) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL28554364 0.89 L3MBTL1 (0.95) L3MBTL1HSP90AA1NPC1CCR1CCR8
Water SCHEMBL10480837 0.89 L3MBTL1 (0.95) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL31020232 0.89 L3MBTL1 (0.95) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL15624642 0.86 L3MBTL1 (0.82) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL21297785 0.84 L3MBTL1 (0.64) L3MBTL1HSP90AA1NPC1CCR1CCR8
SCHEMBL2681389 0.84 L3MBTL1 (0.78) L3MBTL1HSP90AA1NPC1CCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-11063228-B2 Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-07-13 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-12-01 US disclosed
US-20200119288-A1 Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues UNITED STATES DEPARTMENT OF ENERGY 2020-04-16 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS L3MBTL1 661/4885HSP90AA1 226/4885NPC1 4076/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS L3MBTL1 661/4885HSP90AA1 226/4885NPC1 4076/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS L3MBTL1 661/4885HSP90AA1 226/4885NPC1 4076/4885
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials KCNK4, TRPC4, TBRG4 L3MBTL1 1758/4885HSP90AA1 1287/4885NPC1 4601/4885
US-20200119288-A1 Metal-Assisted Delayed Fluorescent Emitters Employing Benzo-imidazo-phenanthridine and Analogues IK, HELZ, SUN2 L3MBTL1 1734/4885HSP90AA1 2330/4885NPC1 3036/4885
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials NT5C, HTR3D, IK L3MBTL1 1948/4885HSP90AA1 773/4885NPC1 2661/4885
US-11063228-B2 Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues IK, HELZ, SUN2 L3MBTL1 1734/4885HSP90AA1 2330/4885NPC1 3036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.