Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29937655 | 1.00 | TRPV4 (0.58) | TRPV4NFE2L2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL24400761 | 0.88 | TRPV4 (0.47) | TRPV4ALDH1A1CYP19A1L3MBTL1 | |
| Pyridine SCHEMBL20135748 | 0.87 | TRPV4 (0.46) | TRPV4KDM4EALDH1A1P2RX7CYP19A1 | |
| SCHEMBL25886965 | 0.82 | NFE2L2 (0.41) | TRPV4NFE2L2CYP19A1ADRA2AKCNH2 | |
| SCHEMBL21994683 | 0.82 | TRPV4 (0.39) | TRPV4NFE2L2ALDH1A1CYP19A1ADRA2A | |
| SCHEMBL25012763 | 0.82 | TRPV4 (0.39) | TRPV4NFE2L2CYP19A1ADRA2AL3MBTL1 | |
| SCHEMBL25894823 | 0.82 | TRPV4 (0.39) | TRPV4NFE2L2CYP19A1ADRA2AKCNH2 | |
| SCHEMBL24400564 | 0.81 | LCK (0.44) | TRPV4P2RX3ADRA2ACNR1CNR2 | |
| SCHEMBL26107386 | 0.81 | ABL1 (0.48) | TRPV4KDM4EADRA2AL3MBTL1ADRA2B | |
| SCHEMBL24400563 | 0.79 | P2RX7 (0.41) | TRPV4P2RX7P2RX3CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118284105-A | Composite material, preparation method thereof, light-emitting device and display device | TCL科技集团股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| EP-2831044-B1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | DOW AGROSCIENCES LLC (US) | 2020-11-11 | — | — | EP | claimed |
| EP-2831044-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | Dow AgroSciences LLC (US) | 2015-02-04 | — | — | EP | claimed |
| CN-104321310-A | Process for preparing 3-substituted-6-trifluoromethylpyridines and process for using 6-trichloromethyl halopyridines | DOW AGROSCIENCES LLC | 2015-01-28 | — | — | CN | claimed |
| US-8785650-B2 | Methods for preparing 3-substituted-6-trifluoromethyl pyridines and methods for using 6-trichloromethyl halogenated pyridines | DOW AGROSCIENCES, LLC. (US) | 2014-07-22 | — | — | US | claimed |
| US-20130261310-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | CORTEVA AGRISCIENCE LLC | 2013-10-03 | — | — | US | claimed |
| WO-2013148338-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | DOW AGROSCIENCES LLC (US) | 2013-10-03 | — | — | WO | claimed |
| US-12538924-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA CROP PROTECTION AG (CH) | 2026-02-03 | — | — | US | disclosed |
| US-20250092016-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2025-03-20 | — | — | US | disclosed |
| CN-111057024-B | Sydney ketone and Sydney ketimine compound, and preparation method and application thereof | 华东理工大学 | 2025-02-07 | — | — | CN | disclosed |
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2025-01-30 | — | — | US | disclosed |
| EP-4415706-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | Vanqua Bio, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| CN-118284105-A | Composite material, preparation method thereof, light-emitting device and display device | TCL科技集团股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| WO-2009078983-A1 | TETRAHYDROCYCLOPENTA[B]INDOL-3-YL CARBOXYLIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2009-06-25 | — | — | WO | disclosed |
| US-7504508-B2 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-03-17 | — | — | US | disclosed |
| US-20090023782-A1 | INCREASING PLANT VIGOR | DOW AGROSCIENCES LLC (IN) | 2009-01-22 | — | — | US | disclosed |
| EP-1740547-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-01-10 | — | — | EP | disclosed |
| US-20060286404-A1 | Light emission material and organic electroluminescent device using the same | AU OPTRONICS CORP. (TW) | 2006-12-21 | — | — | US | disclosed |
| US-20050256158-A1 | PGD2 receptor antagonists for the treatment of inflammatory diseases | MILLENNIUM PHARMACEUTICALS, INC. | 2005-11-17 | — | — | US | disclosed |
| WO-2005100321-A1 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034170-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | GBA1, GAA, GBA2 | TRPV4 4167/4885NFE2L2 2691/4885HSD17B10 1484/4885 |
| US-20090023782-A1 | INCREASING PLANT VIGOR | HDLBP, VPS4B, VPS28 | TRPV4 3503/4885NFE2L2 855/4885HSD17B10 1157/4885 |
| US-12538924-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | CBR3, CBR1, CYCS | TRPV4 2936/4885NFE2L2 1878/4885HSD17B10 1576/4885 |
| US-20130261310-A1 | METHODS FOR PREPARING 3-SUBSTITUTED-6-TRIFLUOROMETHYL PYRIDINES AND METHODS FOR USING 6-TRICHLOROMETHYL HALOGENATED PYRIDINES | CYP4F3, CBR3, PRDX6 | TRPV4 4466/4885NFE2L2 3688/4885HSD17B10 2934/4885 |
| US-20250092016-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | ACE2, ACE, TMPRSS2 | TRPV4 4257/4885NFE2L2 991/4885HSD17B10 576/4885 |
| US-20050256158-A1 | PGD2 receptor antagonists for the treatment of inflammatory diseases | PTGDR2, LTB4R2, CYSLTR2 | TRPV4 860/4885NFE2L2 460/4885HSD17B10 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.