SCHEMBL21297830

SCHEMBL21297830

c1ccc2cc3c(cc2c1)c1nccnc1c1c2ccccc2c2ccccc2c31

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.41
CCR1 P32246 4/20 0.41
CCR8 P51685 4/20 0.41
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 3/20 0.39
CYP1A2 P05177 2/20 0.39
HPGD P15428 2/20 0.39
THRB P10828 1/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 3/20 0.36
HSP90AA1 P07900 2/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 3/20 0.35
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
PMP22 Q01453 2/20 0.34
CCR5 P51681 2/20 0.34
TSHR P16473 2/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21298337 0.85 ALDH1A1 (0.47) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21298192 0.84 ALDH1A1 (0.48) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21298469 0.84 L3MBTL1 (0.43) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21298077 0.84 ALDH1A1 (0.50) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21298198 0.82 ALDH1A1 (0.41) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21297828 0.82 CCR1 (0.45) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21298193 0.82 CCR1 (0.45) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21298015 0.80 CCR1 (0.55) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
Anthracene SCHEMBL6762141 0.80 ALDH1A1 (0.52) L3MBTL1CCR1CCR8ALDH1A1HSD17B10
SCHEMBL21298467 0.80 HSP90AA1 (0.41) L3MBTL1CCR1CCR8ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-12-01 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS L3MBTL1 661/4885CCR1 3636/4885CCR8 3638/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS L3MBTL1 661/4885CCR1 3636/4885CCR8 3638/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS L3MBTL1 661/4885CCR1 3636/4885CCR8 3638/4885
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials KCNK4, TRPC4, TBRG4 L3MBTL1 1758/4885CCR1 4648/4885CCR8 4743/4885
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials NT5C, HTR3D, IK L3MBTL1 1948/4885CCR1 4021/4885CCR8 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.