Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300918 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EPKMMEN1 | |
| SCHEMBL21300945 | 0.78 | KMO (0.49) | ALDH1A1MAPTKDM4ES1PR1CTSS | |
| SCHEMBL21300992 | 0.76 | AR (0.52) | ALDH1A1MAPTKDM4EPKMCTSS | |
| SCHEMBL21301065 | 0.75 | KMO (0.41) | MPLALDH1A1MAPTKDM4ES1PR1 | |
| SCHEMBL21301089 | 0.75 | ACHE (0.42) | MPLMAPTS1PR1 | |
| SCHEMBL18724169 | 0.75 | MAPT (0.39) | MAPTS1PR1CTSSSMN1; SMN2 | |
| SCHEMBL21301076 | 0.74 | MAPT (0.43) | ALDH1A1MAPTKDM4ES1PR1KMT2A | |
| SCHEMBL18724210 | 0.73 | MAPK1 (0.42) | MPLALDH1A1MAPTS1PR1CTSS | |
| SCHEMBL21301171 | 0.72 | KMO (0.40) | MPLS1PR1CTSSMEN1KMT2A | |
| SCHEMBL18691883 | 0.69 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ES1PR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963036-B1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE AND SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2019-08-28 | — | — | EP | disclosed |