Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.39 |
| ▸ | TTK | P33981 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637537 | 0.83 | GABRG2 (0.37) | TTKGABRG2GABRB3GABRA5GPR119 | |
| SCHEMBL22960801 | 0.83 | MAPT (0.39) | TTKGABRG2GABRB3GABRA5MAPT | |
| SCHEMBL16637427 | 0.83 | MAPT (0.41) | TTKGABRG2GABRB3GABRA5MAPT | |
| SCHEMBL21308367 | 0.79 | MAPT (0.36) | TTKGABRG2GABRB3GABRA5MAPT | |
| SCHEMBL19805011 | 0.77 | GABRG2 (0.37) | GABRG2GABRB3GABRA5GPR119GABRA1 | |
| SCHEMBL19806740 | 0.74 | DDB1 (0.42) | GABRG2GABRB3GABRA5GPR119GABRA1 | |
| SCHEMBL23010089 | 0.71 | GABRG2 (0.38) | TTKGABRG2GABRB3GABRA5MAPT | |
| SCHEMBL29773883 | 0.69 | CHRM2 (0.49) | GABRG2GABRB3GABRA5GPR119GABRA1 | |
| SCHEMBL16597821 | 0.69 | GABRG2 (0.42) | GABRG2GABRB3GABRA5GPR119GABRA1 | |
| SCHEMBL1424086 | 0.69 | PRKD1 (0.62) | PRKCAPRKCDPRKD1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10835624-B2 | Compounds for imaging Tau protein aggregates | AC IMMUNE S.A. (CH) | 2020-11-17 | — | — | US | disclosed |
| US-20190262480-A1 | COMPOUNDS FOR IMAGING TAU PROTEIN AGGREGATES | Lantheus Biosciences Ltd. (GB) | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262480-A1 | COMPOUNDS FOR IMAGING TAU PROTEIN AGGREGATES | MAPT, PSEN2, PSEN1 | AAK1 1663/4885TTK 3024/4885GABRG2 2609/4885 |
| US-10835624-B2 | Compounds for imaging Tau protein aggregates | MAPT, PSEN2, PSEN1 | AAK1 1663/4885TTK 3024/4885GABRG2 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.