Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224505 | 0.79 | MAPT (0.89) | MAPTALOX15SIRT2KDM4EATM | |
| SCHEMBL783228 | 0.77 | MAPT (0.57) | MAPTALOX15SIRT2KDM4EATM | |
| SCHEMBL17283743 | 0.75 | GPR3 (0.58) | MAPTALOX15KDM4EPOLBKMT2A | |
| SCHEMBL12109319 | 0.74 | MAPT (0.81) | MAPTALOX15SIRT2KDM4EATM | |
| SCHEMBL31914 | 0.74 | MAPT (1.00) | MAPTALOX15SIRT2KDM4EATM | |
| SCHEMBL21315862 | 0.74 | MAPT (0.40) | MAPTALDH1A1HPGDDHODH | |
| SCHEMBL18201519 | 0.74 | MAPT (0.45) | MAPTALOX15KDM4EATMGAA | |
| SCHEMBL17283591 | 0.74 | ALDH1A1 (0.54) | MAPTALOX15SIRT2KDM4EATM | |
| SCHEMBL19065779 | 0.73 | MAPT (0.79) | MAPTALOX15SIRT2KDM4EATM | |
| SCHEMBL2787546 | 0.73 | MAPT (0.56) | MAPTALOX15SIRT2KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11005047-B2 | Heteroaromatic compound and organic electroluminescence device using the same | LUMINESCENCE TECHNOLOGY CORP. (TW) | 2021-05-11 | — | — | US | disclosed |
| US-11005047-B2 | Heteroaromatic compound and organic electroluminescence device using the same | LUMINESCENCE TECHNOLOGY CORP. (TW) | 2021-05-11 | — | — | US | disclosed |
| US-10844043-B2 | Heteroaromatic compound and organic electroluminescence device using the same | LUMINESCENCE TECHNOLOGY CORP. (TW) | 2020-11-24 | — | — | US | disclosed |
| US-10844043-B2 | Heteroaromatic compound and organic electroluminescence device using the same | LUMINESCENCE TECHNOLOGY CORP. (TW) | 2020-11-24 | — | — | US | disclosed |
| US-20190348609-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2019-11-14 | — | — | US | disclosed |
| US-20190348609-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2019-11-14 | — | — | US | disclosed |
| US-20190322641-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2019-10-24 | — | — | US | disclosed |
| US-20190322641-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2019-10-24 | — | — | US | disclosed |
| US-20190273210-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2019-09-05 | — | — | US | disclosed |
| US-20190273210-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2019-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844043-B2 | Heteroaromatic compound and organic electroluminescence device using the same | VDAC1, TRPC6, TRPC5 | MAPT 1876/4885ALOX15 1041/4885SIRT2 3026/4885 |
| US-11005047-B2 | Heteroaromatic compound and organic electroluminescence device using the same | ARNT, TRPC6, DDT | MAPT 1888/4885ALOX15 756/4885SIRT2 2806/4885 |
| US-20190322641-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | VDAC1, TRPC6, TRPC5 | MAPT 1876/4885ALOX15 1041/4885SIRT2 3026/4885 |
| US-20190348609-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | ARNT, TRPC6, DDT | MAPT 1888/4885ALOX15 756/4885SIRT2 2806/4885 |
| US-20190273210-A1 | HETEROAROMATIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | VDAC1, TRPC6, TRPC5 | MAPT 1876/4885ALOX15 1041/4885SIRT2 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.