Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13494176 | 0.87 | GPR35 (0.39) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL21316426 | 0.85 | MEN1 (0.34) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL12038326 | 0.84 | MEN1 (0.33) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL12038332 | 0.81 | MAOB (0.34) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL31114132 | 0.81 | MAOA (0.40) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL12038299 | 0.80 | MEN1 (0.39) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL21316428 | 0.77 | GPR35 (0.58) | GPR35MAOBMAOAALDH1A1HPGD | |
| SCHEMBL31114267 | 0.76 | GPR35 (0.44) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL12038291 | 0.76 | MEN1 (0.37) | MEN1KMT2AGPR35MAOBMAOA | |
| SCHEMBL12038365 | 0.76 | MEN1 (0.31) | MEN1KMT2AMAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399964-B2 | Coumarin-linked taxanes for detection and circumvention of cellular efflux | THE UNIVERSITY OF KANSAS (US) | 2019-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399964-B2 | Coumarin-linked taxanes for detection and circumvention of cellular efflux | SLC6A1, ABCB11, SLC6A11 | MEN1 1468/4885KMT2A 4818/4885GPR35 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.